node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gpt | b0469 | b0238 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | 0.972 |
apt | guaD | b0469 | b2883 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | 0.908 |
apt | hpt | b0469 | b0125 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis | Hypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine | 0.969 |
apt | rihB | b0469 | b2162 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis | Pyrimidine-specific ribonucleoside hydrolase rihb; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine | 0.910 |
gpt | apt | b0238 | b0469 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis | 0.972 |
gpt | guaD | b0238 | b2883 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | 0.903 |
gpt | hpt | b0238 | b0125 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Hypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine | 0.982 |
gpt | paoC | b0238 | b0284 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Putative xanthine dehydrogenase YagR molybdenum-binding subunit; Enzyme; Not classified; Belongs to the xanthine dehydrogenase family | 0.900 |
gpt | rihB | b0238 | b2162 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Pyrimidine-specific ribonucleoside hydrolase rihb; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine | 0.903 |
gpt | xapA | b0238 | b2407 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Purine nucleoside phosphorylase 2; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. This protein can degrade all purine nucleosides including xanthosine, inosine and guanosine, but cannot cleave adenosine, deoxyadenosine or hypoxanthine arabinoside. Has a preference for the neutral over the monoanionic form of xanthosine | 0.914 |
gpt | xdhA | b0238 | b2866 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Putative xanthine dehydrogenase molybdenum-binding subunit xdha; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism). Deletion results in increased adenine sensitivity, suggesting that this protein contributes to the conversion of adenine to guanine nucleotides during purine salvage | 0.900 |
gpt | xdhB | b0238 | b2867 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Putative xanthine dehydrogenase fad-binding subunit xdhb; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) | 0.907 |
gpt | xdhC | b0238 | b2868 | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | Putative xanthine dehydrogenase iron-sulfur-binding subunit xdhc; Iron-sulfur subunit of the xanthine dehydrogenase complex | 0.900 |
guaD | apt | b2883 | b0469 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis | 0.908 |
guaD | gpt | b2883 | b0238 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Xanthine-guanine phsophoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine | 0.903 |
guaD | hpt | b2883 | b0125 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Hypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine | 0.912 |
guaD | paoC | b2883 | b0284 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Putative xanthine dehydrogenase YagR molybdenum-binding subunit; Enzyme; Not classified; Belongs to the xanthine dehydrogenase family | 0.903 |
guaD | rihB | b2883 | b2162 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Pyrimidine-specific ribonucleoside hydrolase rihb; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine | 0.907 |
guaD | ssnA | b2883 | b2879 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Putative chlorohydrolase/aminohydrolase; Putative aminohydrolase SsnA; Protein involved in cell cycle | 0.905 |
guaD | xapA | b2883 | b2407 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia | Purine nucleoside phosphorylase 2; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. This protein can degrade all purine nucleosides including xanthosine, inosine and guanosine, but cannot cleave adenosine, deoxyadenosine or hypoxanthine arabinoside. Has a preference for the neutral over the monoanionic form of xanthosine | 0.908 |