node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
pssA | trmI | b2585 | b2960 | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | tRNA m(7)G46 methyltransferase, SAM-dependent; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.528 |
pssA | yggL | b2585 | b2959 | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | DUF469 family protein; To H.influenzae HI_0341. | 0.571 |
trmI | pssA | b2960 | b2585 | tRNA m(7)G46 methyltransferase, SAM-dependent; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | 0.528 |
trmI | yggL | b2960 | b2959 | tRNA m(7)G46 methyltransferase, SAM-dependent; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | DUF469 family protein; To H.influenzae HI_0341. | 0.851 |
trpR | yacL | b4393 | b0119 | Transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | UPF0231 family protein. | 0.679 |
trpR | yejK | b4393 | b2186 | Transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | Protein present in spermidine nucleoids. | 0.520 |
trpR | yggL | b4393 | b2959 | Transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | DUF469 family protein; To H.influenzae HI_0341. | 0.591 |
trpR | yihI | b4393 | b3866 | Transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | Activator of Der GTPase; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function, negatively regulating cell growth, probably via ribosome assembly. Stimulates the GTPase activity of Der; a construct missing the first 45 residues is even more stimulatory. Does not stimulate 2 other GTPases (ObgE and Era). Overexpression inhibits cell growth; precursor 16S rRNA accumulates, the 23S rRNA is 6-7 bases longer than usual, and 50S ribosomal subunits are improperly assembled, leading to 45S subunits lacking proteins L9, L18 and L25. Overexpression of Der in the same cells sup [...] | 0.701 |
yacL | trpR | b0119 | b4393 | UPF0231 family protein. | Transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | 0.679 |
yacL | yggL | b0119 | b2959 | UPF0231 family protein. | DUF469 family protein; To H.influenzae HI_0341. | 0.562 |
ybgS | yggL | b0753 | b2959 | Putative homeobox protein. | DUF469 family protein; To H.influenzae HI_0341. | 0.602 |
ydiJ | yfdQ | b1687 | b2360 | Putative FAD-linked oxidoreductase; Putative oxidase. | CPS-53 (KpLE1) prophage; uncharacterized protein. | 0.600 |
ydiJ | yggL | b1687 | b2959 | Putative FAD-linked oxidoreductase; Putative oxidase. | DUF469 family protein; To H.influenzae HI_0341. | 0.730 |
ydiJ | yjgA | b1687 | b4234 | Putative FAD-linked oxidoreductase; Putative oxidase. | Ribosome-associated UPF0307 family protein; Putative alpha helix protein; Protein involved in ATP-binding cassette (ABC) transporter activity. | 0.530 |
yejK | trpR | b2186 | b4393 | Protein present in spermidine nucleoids. | Transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | 0.520 |
yejK | yggL | b2186 | b2959 | Protein present in spermidine nucleoids. | DUF469 family protein; To H.influenzae HI_0341. | 0.637 |
yejK | yihI | b2186 | b3866 | Protein present in spermidine nucleoids. | Activator of Der GTPase; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function, negatively regulating cell growth, probably via ribosome assembly. Stimulates the GTPase activity of Der; a construct missing the first 45 residues is even more stimulatory. Does not stimulate 2 other GTPases (ObgE and Era). Overexpression inhibits cell growth; precursor 16S rRNA accumulates, the 23S rRNA is 6-7 bases longer than usual, and 50S ribosomal subunits are improperly assembled, leading to 45S subunits lacking proteins L9, L18 and L25. Overexpression of Der in the same cells sup [...] | 0.764 |
yfdQ | ydiJ | b2360 | b1687 | CPS-53 (KpLE1) prophage; uncharacterized protein. | Putative FAD-linked oxidoreductase; Putative oxidase. | 0.600 |
yfdQ | yggL | b2360 | b2959 | CPS-53 (KpLE1) prophage; uncharacterized protein. | DUF469 family protein; To H.influenzae HI_0341. | 0.624 |
yfdQ | yjgA | b2360 | b4234 | CPS-53 (KpLE1) prophage; uncharacterized protein. | Ribosome-associated UPF0307 family protein; Putative alpha helix protein; Protein involved in ATP-binding cassette (ABC) transporter activity. | 0.517 |