node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrE | yghS | b3265 | b2985 | Cytoplasmic membrane lipoprotein; Part of the tripartite efflux system AcrEF-TolC. Involved in the efflux of indole and organic solvents. Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative ATP-binding protein; To E.coli YghR and YghT. | 0.441 |
acrE | yghT | b3265 | b2986 | Cytoplasmic membrane lipoprotein; Part of the tripartite efflux system AcrEF-TolC. Involved in the efflux of indole and organic solvents. Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative ATP-binding protein; To E.coli YghR and YghS. | 0.706 |
acrE | yhdU | b3265 | b3263 | Cytoplasmic membrane lipoprotein; Part of the tripartite efflux system AcrEF-TolC. Involved in the efflux of indole and organic solvents. Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative membrane protein. | 0.738 |
dkgA | yghS | b3012 | b2985 | 2,5-diketo-D-gluconate reductase A; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives; Belongs to the aldo/keto reductase family. | Putative ATP-binding protein; To E.coli YghR and YghT. | 0.543 |
dkgA | yghT | b3012 | b2986 | 2,5-diketo-D-gluconate reductase A; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives; Belongs to the aldo/keto reductase family. | Putative ATP-binding protein; To E.coli YghR and YghS. | 0.529 |
dkgA | yheT | b3012 | b3353 | 2,5-diketo-D-gluconate reductase A; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives; Belongs to the aldo/keto reductase family. | UPF0017 family putative hydrolase; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | 0.404 |
holB | yghR | b1099 | b2984 | DNA polymerase III, delta prime subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The gamma complex (gamma(3),delta,delta') is thought to load beta dimers onto DNA by binding ATP which alters the complex's conformation so it can bind beta sliding clamp dimers and open them at one interface. Pr [...] | Putative ATP-binding protein; To E.coli YghS and YghT. | 0.476 |
holB | yghS | b1099 | b2985 | DNA polymerase III, delta prime subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The gamma complex (gamma(3),delta,delta') is thought to load beta dimers onto DNA by binding ATP which alters the complex's conformation so it can bind beta sliding clamp dimers and open them at one interface. Pr [...] | Putative ATP-binding protein; To E.coli YghR and YghT. | 0.476 |
holB | yghT | b1099 | b2986 | DNA polymerase III, delta prime subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The gamma complex (gamma(3),delta,delta') is thought to load beta dimers onto DNA by binding ATP which alters the complex's conformation so it can bind beta sliding clamp dimers and open them at one interface. Pr [...] | Putative ATP-binding protein; To E.coli YghR and YghS. | 0.476 |
purL | yghR | b2557 | b2984 | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Putative ATP-binding protein; To E.coli YghS and YghT. | 0.558 |
purL | yghS | b2557 | b2985 | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Putative ATP-binding protein; To E.coli YghR and YghT. | 0.558 |
purL | yghT | b2557 | b2986 | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Putative ATP-binding protein; To E.coli YghR and YghS. | 0.558 |
ttdR | yghS | b3060 | b2985 | Transcriptional activator of ttdABT; Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon. | Putative ATP-binding protein; To E.coli YghR and YghT. | 0.644 |
ttdR | yghT | b3060 | b2986 | Transcriptional activator of ttdABT; Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon. | Putative ATP-binding protein; To E.coli YghR and YghS. | 0.644 |
ttdR | yheT | b3060 | b3353 | Transcriptional activator of ttdABT; Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon. | UPF0017 family putative hydrolase; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | 0.504 |
yghR | holB | b2984 | b1099 | Putative ATP-binding protein; To E.coli YghS and YghT. | DNA polymerase III, delta prime subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The gamma complex (gamma(3),delta,delta') is thought to load beta dimers onto DNA by binding ATP which alters the complex's conformation so it can bind beta sliding clamp dimers and open them at one interface. Pr [...] | 0.476 |
yghR | purL | b2984 | b2557 | Putative ATP-binding protein; To E.coli YghS and YghT. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.558 |
yghR | yghS | b2984 | b2985 | Putative ATP-binding protein; To E.coli YghS and YghT. | Putative ATP-binding protein; To E.coli YghR and YghT. | 0.894 |
yghR | yghT | b2984 | b2986 | Putative ATP-binding protein; To E.coli YghS and YghT. | Putative ATP-binding protein; To E.coli YghR and YghS. | 0.833 |
yghR | ygiL | b2984 | b3043 | Putative ATP-binding protein; To E.coli YghS and YghT. | Putative fimbrial-like protein. | 0.540 |