STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygiWHydrogen peroxide and cadmium resistance periplasmic protein; stress-induced OB-fold protein. (130 aa)    
Predicted Functional Partners:
qseC
Quorum sensing sensory histidine kinase in two-component regulatory system with QseB; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation.
 
  
 0.880
ygiV
Transcriptional repressor for mcbR biofilm gene; Represses expression of mcbR.
  
  
 0.833
qseB
Quorum sensing DNA-binding response regulator in two-component regulatory system with QseC; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. Currently it is not known whether this effect is direct or not.
  
  
 0.752
elaB
Putative membrane-anchored DUF883 family ribosome-binding protein; Belongs to the ElaB/YgaM/YqjD family.
  
  
 0.744
ygaM
Putative membrane-anchored DUF883 family ribosome-binding protein.
  
    0.708
yqjC
DUF1090 family putative periplasmic protein.
   
  
 0.702
yqjD
Membrane-anchored ribosome-binding protein; Upon overexpression inhibits growth.
   
    0.678
yccJ
Uncharacterized protein.
   
    0.667
osmE
Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress.
   
  
 0.657
dps
Fe-binding and storage protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and cop [...]
   
    0.647
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: medium (56%) [HD]