STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqjHNadph-dependent ferric chelate reductase; Plays a role in iron homeostasis under excess nickel conditions (254 aa)    
Predicted Functional Partners:
yqjI
Padr family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression
  
 0.991
ydiE
Hemin uptake protein hemp homolog; To Y.enterocolitica HemP
   
  
 0.894
ybaN
Inner membrane protein YbaN; Orf; Not classified
   
  
 0.888
yncE
Atp-binding protein, periplasmic, function unknown; Uncharacterized protein YncE; Putative receptor
  
  
 0.873
fes
Enterobactin/ferrienterobactin esterase; Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use
  
  
 0.861
ybiX
Fe(ii)-dependent oxygenase superfamily protein; PKHD-type hydroxylase YbiX; Putative enzyme
   
  
 0.762
entC
Isochorismate synthase entc; Involved in the biosynthesis of the siderophore enterobactin (macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine). Catalyzes the reversible conversion of chorismate to isochorismate
 
  
 0.750
yddB
Putative tonb-dependent outer membrane receptor; To H.influenzae HI_1369
     
 0.742
yddA
Vitamin b12/bleomycin/antimicrobial peptide transport system atp-binding/permease protein; Inner membrane ABC transporter ATP-binding protein YddA; Putative transport; Not classified
     
 0.734
fiu
Putative iron siderophore outer membrane transporter; Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Can also transport catechol-substituted cephalosporins. Receptor for microcins M, H47 and E492
 
  
 0.691
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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