STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exuTHexuronate transporter; Aldohexuronate transport system (432 aa)    
Predicted Functional Partners:
exuR
Exu regulon transcriptional regulator; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers
 
   
 0.980
uxaC
Uronate isomerase; Protein involved in carbohydrate catabolic process; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family
 
  
 0.961
uxaA
Altronate dehydratase; Catalyzes the dehydration of D-altronate
 
  
 0.956
uxaB
Altronate oxidoreductase; Protein involved in carbohydrate catabolic process
 
  
 0.945
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate
  
 
 0.834
ecpD
Fimbria adhesin EcpD; Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Tip pilus adhesin, which is required for assembly of EcpA into fibers (By similarity)
      
 0.810
uxuB
D-mannonate oxidoreductase; Protein involved in carbohydrate catabolic process; Belongs to the mannitol dehydrogenase family. UxuB subfamily
 
  
 0.803
ecpE
Probable fimbrial chaperone EcpE; Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
      
 0.774
yfgM
annotation not available
      
 0.773
b0259
CP4-6 prophage; conserved protein;Phage or Prophage Related
      
 0.750
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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