STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exuRHexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. (258 aa)    
Predicted Functional Partners:
exuT
Hexuronate transporter; Aldohexuronate transport system.
 
  
 0.976
lgoR
Putative transcriptional activator for L-galactonate catabolism; May be a positive transcriptional regulator for lgoD and/or lgoT. Is essential for growth on L-galactonate as the sole carbon source.
 
  
 0.902
uxaA
Altronate hydrolase; Catalyzes the dehydration of D-altronate.
 
   
 0.846
uxaC
Uronate isomerase; Protein involved in carbohydrate catabolic process; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
  
  
 0.824
uxuA
Mannonate hydrolase; Catalyzes the dehydration of D-mannonate.
 
   
 0.822
uxaB
Altronate oxidoreductase, NAD-dependent; Altronate oxidoreductase; Protein involved in carbohydrate catabolic process.
     
 0.813
uxuB
D-mannonate oxidoreductase, NAD-dependent; D-mannonate oxidoreductase; Protein involved in carbohydrate catabolic process; Belongs to the mannitol dehydrogenase family. UxuB subfamily.
     
 0.808
dgoR
D-galactonate catabolism operon transcriptional repressor; Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer.
  
   
 0.790
nanR
Sialic acid-inducible nan operon repressor; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. Represses expression of the nanATEK- yhcH, nanCMS and yjhBC operons. Acts by binding directly to the Nan box, a region of approximately 30 bp covering the promoter region.
  
  
 0.771
yieP
Putative transcriptional regulator.
  
    0.760
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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