node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dsdX | yhaJ | b2365 | b3105 | D-serine transporter; A D-serine-specific transporter, may function as a H(+) symporter. | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | 0.530 |
dsdX | yhaO | b2365 | b3110 | D-serine transporter; A D-serine-specific transporter, may function as a H(+) symporter. | Putative transporter; Plays a role in L-cysteine detoxification. May transport both D- and L-serine (By similarity). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. | 0.654 |
insD1-3 | yhaJ | b1996 | b3105 | CP4-44 prophage; putative disrupted hemin or colicin receptor;Phage or Prophage Related; interrupted by IS2 and C-terminal deletion. | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | 0.499 |
ybiJ | ygiD | b0802 | b3039 | DUF1471 family putative periplasmic protein. | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | 0.740 |
ybiJ | yhaJ | b0802 | b3105 | DUF1471 family putative periplasmic protein. | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | 0.575 |
ybiJ | yhaK | b0802 | b3106 | DUF1471 family putative periplasmic protein. | Redox-sensitive bicupin; Does not have quercetin 2,3-dioxygenase activity. Belongs to the pirin family. | 0.879 |
ybiJ | yhhW | b0802 | b3439 | DUF1471 family putative periplasmic protein. | Quercetinase activity in vitro; Has quercetin 2,3-dioxygenase activity in vitro. Its physiological role is unknown; however, may provide a mechanism that would avoid inhibition of key cellular proteins, such as DNA gyrase, by quercetin. | 0.645 |
ybiJ | yqjF | b0802 | b3101 | DUF1471 family putative periplasmic protein. | Putative quinol oxidase subunit. | 0.808 |
yfeR | yhaJ | b2409 | b3105 | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | 0.555 |
yfeR | yijO | b2409 | b3954 | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.685 |
ygiD | ybiJ | b3039 | b0802 | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | DUF1471 family putative periplasmic protein. | 0.740 |
ygiD | yhaJ | b3039 | b3105 | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | 0.552 |
ygiD | yhaK | b3039 | b3106 | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | Redox-sensitive bicupin; Does not have quercetin 2,3-dioxygenase activity. Belongs to the pirin family. | 0.791 |
ygiD | yhhW | b3039 | b3439 | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | Quercetinase activity in vitro; Has quercetin 2,3-dioxygenase activity in vitro. Its physiological role is unknown; however, may provide a mechanism that would avoid inhibition of key cellular proteins, such as DNA gyrase, by quercetin. | 0.820 |
ygiD | yqjF | b3039 | b3101 | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | Putative quinol oxidase subunit. | 0.595 |
yhaJ | dsdX | b3105 | b2365 | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | D-serine transporter; A D-serine-specific transporter, may function as a H(+) symporter. | 0.530 |
yhaJ | insD1-3 | b3105 | b1996 | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | CP4-44 prophage; putative disrupted hemin or colicin receptor;Phage or Prophage Related; interrupted by IS2 and C-terminal deletion. | 0.499 |
yhaJ | ybiJ | b3105 | b0802 | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | DUF1471 family putative periplasmic protein. | 0.575 |
yhaJ | yfeR | b3105 | b2409 | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | 0.555 |
yhaJ | ygiD | b3105 | b3039 | LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). | 4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown. | 0.552 |