STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaJLysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity). (298 aa)    
Predicted Functional Partners:
yhaK
Redox-sensitive bicupin; Does not have quercetin 2,3-dioxygenase activity. Belongs to the pirin family.
 
 
 
 0.964
yqjF
Putative quinol oxidase subunit.
      
 0.902
yhaO
Putative transporter; Plays a role in L-cysteine detoxification. May transport both D- and L-serine (By similarity). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
      
 0.893
yhhW
Quercetinase activity in vitro; Has quercetin 2,3-dioxygenase activity in vitro. Its physiological role is unknown; however, may provide a mechanism that would avoid inhibition of key cellular proteins, such as DNA gyrase, by quercetin.
  
   
 0.705
ybiJ
DUF1471 family putative periplasmic protein.
      
 0.575
yfeR
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
  
  
 0.555
ygiD
4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown.
      
 0.552
dsdX
D-serine transporter; A D-serine-specific transporter, may function as a H(+) symporter.
      
 0.530
yijO
Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription.
   
  
 0.510
insD1-3
CP4-44 prophage; putative disrupted hemin or colicin receptor;Phage or Prophage Related; interrupted by IS2 and C-terminal deletion.
      
 0.499
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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