node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frlR | psuK | b3375 | b2166 | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). | 0.812 |
frlR | tdcA | b3375 | b3118 | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | 0.533 |
frlR | tdcR | b3375 | b3119 | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | 0.733 |
psuK | frlR | b2166 | b3375 | Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | 0.812 |
psuK | tdcA | b2166 | b3118 | Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | 0.532 |
psuK | tdcR | b2166 | b3119 | Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | 0.733 |
tdcA | frlR | b3118 | b3375 | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | 0.533 |
tdcA | psuK | b3118 | b2166 | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). | 0.532 |
tdcA | tdcB | b3118 | b3117 | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | L-threonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine t [...] | 0.955 |
tdcA | tdcR | b3118 | b3119 | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | 0.963 |
tdcB | tdcA | b3117 | b3118 | L-threonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine t [...] | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | 0.955 |
tdcB | tdcR | b3117 | b3119 | L-threonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine t [...] | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | 0.550 |
tdcR | frlR | b3119 | b3375 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | 0.733 |
tdcR | psuK | b3119 | b2166 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). | 0.733 |
tdcR | tdcA | b3119 | b3118 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | Tdc operon transcriptional activator; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. | 0.963 |
tdcR | tdcB | b3119 | b3117 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | L-threonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine t [...] | 0.550 |
tdcR | ydeO | b3119 | b1499 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | UV-inducible global regulator, EvgA-, GadE-dependent; Induces the expression of gadE and mdtEF. Could also regulate the expression of other genes involved in acid resistance. | 0.536 |
tdcR | yhaB | b3119 | b3120 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | Uncharacterized protein. | 0.600 |
tdcR | yhaC | b3119 | b3121 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | Pentapetide repeats-related protein. | 0.547 |
tdcR | yhhZ | b3119 | b3442 | L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon. | Putative Hcp1 family polymorphic toxin protein; putative colicin-like DNase/tRNase activity; Belongs to the hcp1 family. | 0.528 |