node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
garK | garL | b3124 | b3126 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. | 0.792 |
garK | garR | b3124 | b3125 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | 0.984 |
garK | ghrA | b3124 | b1033 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | 0.900 |
garK | ghrB | b3124 | b3553 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2- keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D- fructose and L-sorbose. Activity with NAD is very low; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.909 |
garK | glxK | b3124 | b0514 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Glycerate kinase II; Protein involved in carbohydrate catabolic process, glycolate metabolic process and allantoin assimilation pathway; Belongs to the glycerate kinase type-1 family. | 0.908 |
garK | glxR | b3124 | b0509 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Tartronate semialdehyde reductase, NADH-dependent; Protein involved in carbohydrate catabolic process, glycolate metabolic process and allantoin assimilation pathway; Belongs to the HIBADH-related family. | 0.946 |
garK | gpmA | b3124 | b0755 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.902 |
garK | gpmM | b3124 | b3612 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Phosphoglycero mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate (2-PGA) and 3-phosphoglycerate (3-PGA). | 0.907 |
garK | tadA | b3124 | b2559 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2). Essential for cell viability. Belongs to the cytidine and deoxycytidylate deaminase family. | 0.884 |
garK | ytjC | b3124 | b4395 | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | Phosphatase; Phosphoglyceromutase 2; Protein involved in glycolysis and gluconeogenesis; Belongs to the phosphoglycerate mutase family. GpmB subfamily. | 0.900 |
garL | garK | b3126 | b3124 | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | 0.792 |
garL | garR | b3126 | b3125 | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | 0.999 |
garL | glxR | b3126 | b0509 | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. | Tartronate semialdehyde reductase, NADH-dependent; Protein involved in carbohydrate catabolic process, glycolate metabolic process and allantoin assimilation pathway; Belongs to the HIBADH-related family. | 0.918 |
garR | garK | b3125 | b3124 | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | 0.984 |
garR | garL | b3125 | b3126 | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. | 0.999 |
garR | ghrA | b3125 | b1033 | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | 0.901 |
garR | ghrB | b3125 | b3553 | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2- keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D- fructose and L-sorbose. Activity with NAD is very low; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.939 |
garR | glxK | b3125 | b0514 | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | Glycerate kinase II; Protein involved in carbohydrate catabolic process, glycolate metabolic process and allantoin assimilation pathway; Belongs to the glycerate kinase type-1 family. | 0.902 |
garR | glxR | b3125 | b0509 | Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate. | Tartronate semialdehyde reductase, NADH-dependent; Protein involved in carbohydrate catabolic process, glycolate metabolic process and allantoin assimilation pathway; Belongs to the HIBADH-related family. | 0.907 |
ghrA | garK | b1033 | b3124 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | Glycerate kinase I; Protein involved in carbohydrate catabolic process; Belongs to the glycerate kinase type-1 family. | 0.900 |