STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garPPutative (D)-galactarate transporter; Uptake of D-galactarate; Belongs to the major facilitator superfamily. Phthalate permease family. (444 aa)    
Predicted Functional Partners:
garL
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
 
    0.972
garR
Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate.
  
    0.906
garD
D-galactarate dehydrogenase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
    0.875
gudX
Glucarate dehydratase-related protein, substrate unknown; Does not seem to have an in-vivo activity on glucarate or idarate. Its real substrate is unknown.
 
  
 0.806
ynfO
Uncharacterized protein YnfO; Pseudogene, Qin prophage; Phage DNA packaging protein Nu1 family;Phage or Prophage Related; DNA packaging protein NU1 homolog from lambdoid prophage Qin.
      
 0.803
gudP
Putative D-glucarate transporter; Uptake of D-glucarate; Belongs to the major facilitator superfamily. Phthalate permease family.
  
   
0.802
rhmT
Putative L-rhamnonate transporter; Putative transport protein; Belongs to the major facilitator superfamily. Phthalate permease family.
  
    0.753
ygaC
Uncharacterized protein.
      
 0.739
kefG
Potassium-efflux system ancillary protein for KefB, glutathione-regulated; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
      
 0.622
kefF
Potassium-efflux system ancillary protein for KefC, glutathione-regulated; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC. Can use a wide range of substrates, including electrophilic quinones, and its function could be to reduce the redox toxicity of electrophilic quinones in parallel with acting as triggers for the KefC efflux system. Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
      
 0.521
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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