STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garPMfs transporter, acs family, probable galactarate transporter; Uptake of D-galactarate (444 aa)    
Predicted Functional Partners:
garL
Alpha-dehydro-beta-deoxy-d-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde
 
    0.957
garD
D-galactarate dehydrogenase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate
 
    0.877
ynfO
Uncharacterized protein YnfO; Pseudogene, Qin prophage; Phage DNA packaging protein Nu1 family;Phage or Prophage Related; DNA packaging protein NU1 homolog from lambdoid prophage Qin
      
 0.867
ygaC
annotation not available
      
 0.823
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate
 
    0.816
gudD
D-glucarate dehydratase 1; Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D- glucarate (5-kdGluc). Also acts on L-idarate
 
   0.761
gudX
Glucarate dehydratase-related protein, substrate unknown; Does not seem to have an in-vivo activity on glucarate or idarate. Its real substrate is unknown
 
 
 0.732
rhmT
Putative l-rhamnonate transporter; Belongs to the major facilitator superfamily. Phthalate permease family
 
    0.622
yahA
Dna-binding transcriptional activator/c-di-gmp phosphodiesterase pdel; Acts both as an enzyme and as a c-di-GMP sensor to couple transcriptional activity to the c-di-GMP status of the cell . Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG Also acts as a transcription factor to control its own expression
     
 0.607
gspC
General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
      
 0.604
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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