STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhbEannotation not available (321 aa)    
Predicted Functional Partners:
obgE
GTPase ObgE/CgtA; An abundant, essential GTPase which binds GTP, GDP and ppGpp with moderate affinity. Has high guanosine nucleotide exchange rate constants for GTP and GDP, and a relatively low GTP hydrolysis rate stimulated by the 50S ribosomal subunit. It is estimated there are 34000 molecules in log-phase cells and 5600 molecules in stationary-phase cells. Required for chromosome segregation. Plays a role in the stringent response, perhaps by sequestering 50S ribosomal subunits and decreasing protein synthesis, and a non-essential role in the late steps of ribosome biogenesis, perh [...]
  
   0.934
yajG
Uncharacterized lipoprotein YajG; Putative polymerase/proteinase
  
   
 0.791
wbbK
Putative glycosyltransferase WbbK; May be a glycosyltransferase involved in the transfer of UDP-GalF and UDP-glucose
   
 
 0.775
metQ
D-methionine-binding lipoprotein MetQ; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system; Belongs to the NlpA lipoprotein family
      
 0.744
purK
N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family
      
 0.740
pspG
Phage shock protein G; Effector of the phage shock response
  
   
 0.720
rpmA
50S ribosomal protein L27; Protein involved in structural constituent of ribosome and translation
  
    0.626
ycbJ
annotation not available
  
     0.610
carB
Carbamoyl-phosphate synthase large chain; Protein involved in arginine biosynthetic process and pyrimidine nucleotide biosynthetic process; Belongs to the CarB family
   
  
 0.597
pspF
Psp operon transcriptional activator; Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene
      
 0.591
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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