STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltFInvolved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon (254 aa)    
Predicted Functional Partners:
yhcA
Could be required for the biogenesis of a putative fimbria.
 
  
 0.952
yhcD
Involved in the export and assembly of a fimbrial subunit across the outer membrane
 
   
 0.943
gltD
Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate
      
 0.877
gltB
Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate
      
 0.872
gltS
Catalyzes the sodium-dependent, binding-protein-independent transport of glutamate. ECO:0000269|PubMed:2537813, ECO:0000269|PubMed:336628,
      
 0.818
mcrA
Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence C(me)CGG
  
     0.722
wbbK
May be a glycosyltransferase involved in the transfer of UDP- GalF and UDP-glucose
  
     0.700
yqiI
May be involved in a fimbrial system chaperoned by YqiH and exported by YqiG
  
     0.659
casA
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
  
     0.654
waaS
Lipopolysaccharide core biosynthesis; Protein involved in cell surface antigen activity, host-interacting and lipopolysaccharide core region biosynthetic process
  
     0.654
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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