STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhcFPutative transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent; To E.coli GltF. (238 aa)    
Predicted Functional Partners:
yhcG
DUF1016 family protein in the PD-(D/E)XK nuclease superfamily; May be a nuclease involved in DNA recombination and repair.
  
  
 0.888
ychE
UPF0056 family inner membrane protein; Putative channel protein.
      
 0.805
yhcA
Putative periplasmic chaperone protein; Could be required for the biogenesis of a putative fimbria. Belongs to the periplasmic pilus chaperone family.
  
  
 0.785
yhcD
Putative outer membrane fimbrial subunit usher protein; Involved in the export and assembly of a fimbrial subunit across the outer membrane; Belongs to the fimbrial export usher family.
  
  
 0.748
yigE
DUF2233 family protein.
      
 0.736
ypfH
palmitoyl-CoA esterase activity, uncertain physiological substrate; Displays esterase activity toward palmitoyl-CoA and pNP- butyrate.
      
 0.731
yhcC
Putative Fe-S oxidoreductase, Radical SAM superfamily protein; In vitro, can cleave S-adenosyl-L-methionine into methionine and 5'-deoxyadenosine (AdoH); Belongs to the radical SAM superfamily.
      
 0.644
ytfL
UPF0053 family inner membrane protein; Putative transport protein.
      
 0.644
ssnA
Putative chlorohydrolase/aminohydrolase; Protein involved in cell cycle.
      
 0.600
ygiL
Putative fimbrial-like protein.
   
  
 0.536
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (28%) [HD]