STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrdABacterial transferase hexapeptide domain protein; Putative transferase; Belongs to the gamma-class carbonic anhydrase family. (184 aa)    
Predicted Functional Partners:
yibA
Putative immunity protein for polymorphic toxin RhsA; HEAT-domain protein; lethality reduction protein.
      
 0.622
can
Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family.
   
 
 0.549
cynT
Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate.
    
 
 0.549
yggC
Putative PanK family P-loop kinase; Putative kinase.
      
 0.524
insJ
IS150 transposase A; Belongs to the IS150/IS1296 orfA family.
      
 0.523
ygfZ
Iron-sulfur cluster repair protein, plumbagin resistance; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.
      
 0.463
ybgJ
Putative allophanate hydrolase, subunit 1; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the PxpB family.
      
 0.456
ybhN
UPF0104 family inner membrane protein.
     
 0.455
yaeR
Putative lyase; To B.subtilis YwkD.
 
    0.449
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
 
  
 0.437
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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