STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prkBProbable phosphoribulokinase; Protein involved in glucose metabolic process. (289 aa)    
Predicted Functional Partners:
yheT
UPF0017 family putative hydrolase; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
  
  
 0.822
yheU
UPF0270 family protein; Belongs to the UPF0270 family.
  
    0.654
yheS
ABC-F family protein predicted regulatory ATPase; Genetic data indicate it may be involved in ribosome assembly or function; Belongs to the ABC transporter superfamily. ABCF family. YheS subfamily.
  
    0.611
yheV
DUF2387 family putative metal-binding protein.
 
     0.554
fbp
Protein involved in gluconeogenesis.
 
  
 0.524
kefB
Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
       0.522
rpe
D-ribulose-5-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate.
  
  
 0.468
kefG
Potassium-efflux system ancillary protein for KefB, glutathione-regulated; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
       0.461
trpL
Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.
      
 0.459
opgD
OPG biosynthetic periplasmic protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
  
     0.420
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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