node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
birA | yhfS | b3973 | b3376 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | 0.732 |
birA | yhfT | b3973 | b3377 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Inner membrane protein; Putative transport system permease protein. | 0.783 |
birA | yigM | b3973 | b3827 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative inner membrane EamA-like transporter; Uptake of biotin. Acts probably by facilitated diffusion. Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family. | 0.632 |
php | yhfS | b3379 | b3376 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | 0.981 |
php | yhfT | b3379 | b3377 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | Inner membrane protein; Putative transport system permease protein. | 0.962 |
php | yhfU | b3379 | b3378 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | DUF2620 family protein. | 0.953 |
php | yhfW | b3379 | b3380 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | Phosphopentomutase-related metalloenzyme superfamily protein; Putative mutase. | 0.980 |
php | yhfX | b3379 | b3381 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | Putative pyridoxal 5'-phosphate binding protein. | 0.989 |
php | yhfY | b3379 | b3382 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | PRD domain protein. | 0.834 |
php | yhfZ | b3379 | b3383 | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | Putative DNA-binding transcriptional regulator. | 0.951 |
yfjK | yhfT | b2627 | b3377 | Radiation resistance protein; DEAD/H helicase-like protein; CP4-57 putative defective prophage. | Inner membrane protein; Putative transport system permease protein. | 0.422 |
yfjK | yhfZ | b2627 | b3383 | Radiation resistance protein; DEAD/H helicase-like protein; CP4-57 putative defective prophage. | Putative DNA-binding transcriptional regulator. | 0.414 |
yhfS | birA | b3376 | b3973 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.732 |
yhfS | php | b3376 | b3379 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | Phosphotriesterase homology protein; Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate. No enzymatic activity was detected with any of these non-specific substrates. | 0.981 |
yhfS | yhfT | b3376 | b3377 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | Inner membrane protein; Putative transport system permease protein. | 0.999 |
yhfS | yhfU | b3376 | b3378 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | DUF2620 family protein. | 0.981 |
yhfS | yhfW | b3376 | b3380 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | Phosphopentomutase-related metalloenzyme superfamily protein; Putative mutase. | 0.971 |
yhfS | yhfX | b3376 | b3381 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | Putative pyridoxal 5'-phosphate binding protein. | 0.993 |
yhfS | yhfY | b3376 | b3382 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | PRD domain protein. | 0.628 |
yhfS | yhfZ | b3376 | b3383 | FNR-regulated pyridoxal phosphate-dependent aminotransferase family protein. | Putative DNA-binding transcriptional regulator. | 0.887 |