STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
livKL-leucine/l-phenylalanine abc transporter periplasmic binding protein; This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids in E.coli (369 aa)    
Predicted Functional Partners:
livF
Branched chain amino acid/phenylalanine abc transporter atp binding subunit livf; Component of the leucine-specific transport system
 0.999
livM
Branched chain amino acid/phenylalanine abc transporter membrane subunit livm; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane
 
 0.999
livH
Branched chain amino acid/phenylalanine abc transporter membrane subunit livh; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane
 
 0.999
livG
Branched chain amino acid/phenylalanine abc transporter atp binding subunit livg; Component of the leucine-specific transport system
 0.998
livJ
Branched chain amino acid/phenylalanine abc transporter periplasmic binding protein; This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high- affinity transport of the branched-chain amino acids
  
 
0.945
gltB
Glutamate synthase (nadph) large chain; Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate
  
  
 0.644
argT
Lysine/arginine/ornithine abc transporter periplasmic binding protein; Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP (By similarity)
  
   
 0.639
glnH
L-glutamine abc transporter periplasmic binding protein; Involved in a glutamine-transport system GlnHPQ
  
   
 0.626
hisJ
Histidine abc transporter periplasmic binding protein; Part of the histidine permease ABC transporter. Binds histidine. Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation (By similarity)
  
   
 0.573
hisP
Lysine/arginine/ornithine abc transporter/histidine abc transporter, atp binding subunit; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Responsible for energy coupling to the transport system (By similarity)
 
    
 0.564
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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