STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsmD16S rRNA m(2)G966 methyltransferase, SAM-dependent; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. (198 aa)    
Predicted Functional Partners:
yhhL
DUF1145 family protein.
 
    0.925
ftsY
Signal Recognition Particle (SRP) receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
 
  
 0.820
rsmC
16S rRNA m(2)G1207 methyltransferase, SAM-dependent; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
   
  
 0.810
rlmG
23S rRNA m(2)G1835 methyltransferase, SAM-dependent; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
   
  
 0.809
rlmL
23S rRNA m(2)G2445 and m(7)G2069 methyltransferases, SAM-dependent; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Methylation occurs before assembly of 23S rRNA into 50S subunits. Belongs to the methyltransferase superfamily. RlmKL family.
   
  
 0.789
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. CoA is not a substrate for the enzyme ; Belongs to the bacterial CoaD family.
 
  
 0.749
yhhN
TMEM86 family putative inner membrane protein; Putative enzyme.
 
    0.692
rluB
23S rRNA pseudouridine(2605) synthase; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
     0.681
ftsE
Cell division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.
  
   0.663
rlmJ
23S rRNA m(6)A2030 methyltransferase, SAM-dependent; Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Required for the utilization of extracellular DNA as the sole source of carbon and energy. Belongs to the RlmJ family.
   
  
 0.645
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.