node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
prpR | yhhM | b0330 | b3467 | Propionate catabolism operon regulatory protein; Involved in the transcriptional regulation of the propionate catabolism operon. | DUF2500 family protein; Putative receptor. | 0.459 |
pth | yhhM | b1204 | b3467 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death. | DUF2500 family protein; Putative receptor. | 0.457 |
rutD | ydcO | b1009 | b1433 | Putative reactive intermediate detoxifying aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation. | BenE family inner membrane putative transporter; Putative membrane transport protein. | 0.457 |
rutD | yhhM | b1009 | b3467 | Putative reactive intermediate detoxifying aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation. | DUF2500 family protein; Putative receptor. | 0.644 |
rutD | yjgZ | b1009 | b4277 | Putative reactive intermediate detoxifying aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation. | Uncharacterized protein YjgZ; Pseudogene fragment. | 0.543 |
wcaJ | yhhM | b2047 | b3467 | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | DUF2500 family protein; Putative receptor. | 0.591 |
ydcO | rutD | b1433 | b1009 | BenE family inner membrane putative transporter; Putative membrane transport protein. | Putative reactive intermediate detoxifying aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation. | 0.457 |
ydcO | yhhM | b1433 | b3467 | BenE family inner membrane putative transporter; Putative membrane transport protein. | DUF2500 family protein; Putative receptor. | 0.802 |
ydcO | yjgZ | b1433 | b4277 | BenE family inner membrane putative transporter; Putative membrane transport protein. | Uncharacterized protein YjgZ; Pseudogene fragment. | 0.735 |
yhhM | prpR | b3467 | b0330 | DUF2500 family protein; Putative receptor. | Propionate catabolism operon regulatory protein; Involved in the transcriptional regulation of the propionate catabolism operon. | 0.459 |
yhhM | pth | b3467 | b1204 | DUF2500 family protein; Putative receptor. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death. | 0.457 |
yhhM | rutD | b3467 | b1009 | DUF2500 family protein; Putative receptor. | Putative reactive intermediate detoxifying aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation. | 0.644 |
yhhM | wcaJ | b3467 | b2047 | DUF2500 family protein; Putative receptor. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.591 |
yhhM | ydcO | b3467 | b1433 | DUF2500 family protein; Putative receptor. | BenE family inner membrane putative transporter; Putative membrane transport protein. | 0.802 |
yhhM | yhhN | b3467 | b3468 | DUF2500 family protein; Putative receptor. | TMEM86 family putative inner membrane protein; Putative enzyme. | 0.538 |
yhhM | yjgZ | b3467 | b4277 | DUF2500 family protein; Putative receptor. | Uncharacterized protein YjgZ; Pseudogene fragment. | 0.819 |
yhhM | zntA | b3467 | b3469 | DUF2500 family protein; Putative receptor. | Zinc, cobalt and lead efflux system; Confers resistance to zinc, cadmium and lead. Couples the hydrolysis of ATP with the export of zinc, cadmium or lead, with highest activity when the metals are present as metal-thiolate complexes. Can also bind nickel, copper, cobalt and mercury. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | 0.406 |
yhhN | yhhM | b3468 | b3467 | TMEM86 family putative inner membrane protein; Putative enzyme. | DUF2500 family protein; Putative receptor. | 0.538 |
yhhN | zntA | b3468 | b3469 | TMEM86 family putative inner membrane protein; Putative enzyme. | Zinc, cobalt and lead efflux system; Confers resistance to zinc, cadmium and lead. Couples the hydrolysis of ATP with the export of zinc, cadmium or lead, with highest activity when the metals are present as metal-thiolate complexes. Can also bind nickel, copper, cobalt and mercury. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | 0.676 |
yjgZ | rutD | b4277 | b1009 | Uncharacterized protein YjgZ; Pseudogene fragment. | Putative reactive intermediate detoxifying aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation. | 0.543 |