STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcrBPutative lipoprotein; Required for phage C1 adsorption. (185 aa)    
Predicted Functional Partners:
yhhQ
DUF165 family inner membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. Transports 7-cyano-7-deazaguanine (preQ(0)) and 7-aminomethyl-7-deazaguanine (preQ(1)), with a preference for preQ(0).
 
    0.851
osmE
Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress.
    
 
 0.731
slp
Outer membrane lipoprotein; The induction of Slp may help to stabilize the outer membrane during carbon starvation and stationary phase.
    
 
 0.664
yajG
Putative polymerase/proteinase.
   
   0.650
yraP
Outer membrane lipoprotein; Putative periplasmic protein.
   
   0.649
moaB
Inactive molybdopterin adenylyltransferase; May be involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity; Belongs to the MoaB/Mog family.
    
   0.645
yciB
IspA family inner membrane protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
      
 0.591
sdaC
Putative serine transporter; Involved in the import of serine into the cell. May be required for phage C1 adsorption by interacting with DrcB. May also be involved in ampicillin sensitivity.
      
 0.519
nrfB
Nitrite reductase, formate-dependent, penta-heme cytochrome c; Plays a role in nitrite reduction.
      
 0.455
fre
NAD(P)H-flavin reductase; Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides; Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
   
  
 0.423
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.