STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikBInvolved in a nickel transport system, probably translocates nickel through the bacterial inner membrane (314 aa)    
Predicted Functional Partners:
nikA
Involved in a nickel transport system, probably represents the nickel binder
 0.999
nikC
Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane
 0.999
nikD
Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
 0.999
nikE
Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
 
 0.999
nikR
Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel
 
 
 
 0.966
dppC
Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane
 
 0.849
ydfA
Uncharacterized protein YdfA; Phage or Prophage Related; To E.coli YdaF
      
 0.822
oppC
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane
 
 
 0.814
ddpC
Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane
 
 
 0.813
gsiD
Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane
 
 
 0.808
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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