STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uspBProtein involved in response to stress and xenobiotic metabolic process. (111 aa)    
Predicted Functional Partners:
uspA
Universal stress global response regulator; Required for resistance to DNA-damaging agents; Belongs to the universal stress protein A family.
  
  
 0.933
uspE
Stress-induced protein; Required for resistance to DNA-damaging agents.
  
  
 0.839
uspD
Stress-induced protein; Required for resistance to DNA-damaging agents.
  
  
 0.828
uspF
Universal stress protein F; Pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related.
  
  
 0.807
ycgB
SpoVR family stationary phase protein; To B.subtilis SpoVR.
   
  
 0.772
yodD
Uncharacterized protein.
   
  
 0.771
uspG
Universal stress protein UP12; Has intrinsic autoadenylation and autophosphorylation activities, probably on Ser or Thr residues. Belongs to the universal stress protein A family.
  
  
 0.770
yhfG
Putative antitoxin for Fic.
   
    0.748
bolA
Stationary-phase morphogene, transcriptional repressor for mreB; Transcriptional regulator that plays an important role in general stress response. Has many effects on cell morphology, cell growth and cell division. Acts by regulating the transcription of many genes, including dacA (PBP-5), dacC (PBP-6), ampC and mreB. Probably involved in the coordination of genes that adapt the cell physiology in order to enhance cell adaptation and survival under stress conditions. Essential for normal cell morphology in stationary phase and under conditions of starvation. Also regulates a complex n [...]
   
  
 0.740
fic
Stationary phase-induced protein, putative toxin; Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP. May have some role in cell division.
   
    0.740
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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