node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alaA | aspC | b2290 | b0928 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Aspartate aminotransferase, PLP-dependent; Aspartate aminotransferase; Protein involved in cellular amino acid catabolic process and aspartate biosynthetic process. | 0.934 |
alaA | avtA | b2290 | b3572 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.981 |
alaA | ilvD | b2290 | b3771 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Dihydroxyacid dehydratase. | 0.915 |
alaA | ilvE | b2290 | b3770 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. | 0.922 |
alaA | leuA | b2290 | b0074 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.920 |
alaC | avtA | b2379 | b3572 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.808 |
aspC | alaA | b0928 | b2290 | Aspartate aminotransferase, PLP-dependent; Aspartate aminotransferase; Protein involved in cellular amino acid catabolic process and aspartate biosynthetic process. | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 0.934 |
aspC | avtA | b0928 | b3572 | Aspartate aminotransferase, PLP-dependent; Aspartate aminotransferase; Protein involved in cellular amino acid catabolic process and aspartate biosynthetic process. | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.670 |
aspC | ilvE | b0928 | b3770 | Aspartate aminotransferase, PLP-dependent; Aspartate aminotransferase; Protein involved in cellular amino acid catabolic process and aspartate biosynthetic process. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. | 0.828 |
aspC | tyrB | b0928 | b4054 | Aspartate aminotransferase, PLP-dependent; Aspartate aminotransferase; Protein involved in cellular amino acid catabolic process and aspartate biosynthetic process. | Tyrosine aminotransferase, tyrosine-repressible, PLP-dependent; Broad-specificity enzyme that catalyzes the transamination of 2-ketoisocaproate, p-hydroxyphenylpyruvate, and phenylpyruvate to yield leucine, tyrosine, and phenylalanine, respectively. In vitro, is able to catalyze the conversion of beta-methyl phenylpyruvate to the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin produced by Streptomyces hygroscopicus NRRL3085; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.918 |
avtA | alaA | b3572 | b2290 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 0.981 |
avtA | alaC | b3572 | b2379 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 0.808 |
avtA | aspC | b3572 | b0928 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Aspartate aminotransferase, PLP-dependent; Aspartate aminotransferase; Protein involved in cellular amino acid catabolic process and aspartate biosynthetic process. | 0.670 |
avtA | ilvC | b3572 | b3774 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Ketol-acid reductoisomerase, NAD(P)-binding; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. Also able to use 2-ketopantoate, 2-ketoisovalerate, 2-ketovalerate, 2-ketobutyrate [...] | 0.673 |
avtA | ilvD | b3572 | b3771 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Dihydroxyacid dehydratase. | 0.952 |
avtA | ilvE | b3572 | b3770 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. | 0.989 |
avtA | leuA | b3572 | b0074 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.958 |
avtA | malS | b3572 | b3571 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Alpha-amylase; Since only maltooligosaccharides up to a chain length of 6 glucose units are actively transported through the cytoplasmic membrane via the membrane-bound complex of three proteins, MalF, MalG, and MalK, longer maltooligosaccharides must first be degraded by the periplasmic alpha-amylase, the MalS protein; Belongs to the glycosyl hydrolase 13 family. | 0.847 |
avtA | tyrB | b3572 | b4054 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Tyrosine aminotransferase, tyrosine-repressible, PLP-dependent; Broad-specificity enzyme that catalyzes the transamination of 2-ketoisocaproate, p-hydroxyphenylpyruvate, and phenylpyruvate to yield leucine, tyrosine, and phenylalanine, respectively. In vitro, is able to catalyze the conversion of beta-methyl phenylpyruvate to the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin produced by Streptomyces hygroscopicus NRRL3085; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.788 |
avtA | xylR | b3572 | b3569 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Xylose divergent operon transcriptional activator; Regulatory protein for the xylBAFGHR operon. | 0.677 |