STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yicJGlycoside/pentoside/hexuronide:cation symporter, gph family; Inner membrane symporter YicJ; Putative permease (460 aa)    
Predicted Functional Partners:
yicI
Alpha-d-xyloside xylohydrolase; Can catalyze the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose and trehalose
 
   0.880
abgR
Putative dna-binding transcriptional regulator of abgabt operon; Could be the regulator of the abg operon
      
 0.737
yhaI
DUF805 family inner membrane protein; Inner membrane protein YhaI; Putative cytochrome
      
 0.733
mhpD
2-hydroxypentadienoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid
      
 0.731
ylbE
DUF1116 domain-containing protein YlbE; To E.coli YahG
      
 0.667
mmuP
S-methyl-l-methionine transporter; Transporter for the intake of S-methylmethionine
      
 0.641
yajO
1-deoxyxylulose-5-phosphate synthase YajO; Catalyzes the conversion of ribulose 5-phosphate (Ru5P) to 1- deoxy-D-xylulose 5-phosphate (DXP), providing a direct route from pentoses to terpenes. May play a role in biosynthesis of DXP under conditions of thiamine starvation
      
 0.605
ygiM
annotation not available
      
 0.560
yraP
Divisome-associated lipoprotein yrap; Uncharacterized protein YraP; Putative periplasmic protein
      
 0.560
treB
Trehalose-specific pts enzyme: iib and iic component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport at low osmolarity
      
 0.473
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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