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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yidKSolute:na+ symporter, sss family; Uncharacterized symporter YidK; Putative cotransporter (571 aa)    
Predicted Functional Partners:
yidJ
Sulfatase/phosphatase superfamily protein; Belongs to the sulfatase family
 
     0.929
yidL
Uncharacterized HTH-type transcriptional regulator YidL; Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription
 
     0.804
yhiJ
annotation not available
      
 0.736
ybfD
H repeat-associated putative transposase ybfd; Belongs to the transposase 11 family
      
 0.673
ydiF
Putative acetyl-coa:acetoacetyl-coa transferase: alpha subunit/beta subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. May play a role in short-chain fatty acid metabolism in E.coli (By similarity)
      
 0.670
ydcC
H repeat-associated putative transposase ydcc; Belongs to the transposase 11 family
      
 0.613
yidR
annotation not available
      
 0.605
fdrA
Putative nad(p)-binding acyl-coa synthetase; Not known; multicopy suppressor of dominant negative ftsH mutations
      
 0.575
sdhE
Flavinator of succinate dehydrogenase; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH Required for flavinylation of the [...]
      
 0.561
nikD
Ni(2(+)) ABC transporter ATP binding subunit NikD; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
      
 0.520
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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