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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yidPUncharacterized HTH-type transcriptional regulator YidP; Pseudogene, arbutin specific enzyme IIC component of PTS;enzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols; PTS system, arbutin-like IIB component; PTS system, arbutin-like IIC component (238 aa)    
Predicted Functional Partners:
yidZ
Putative lysr-type transcriptional regulator yidz; Involved in anaerobic NO protection
      
 0.900
waaS
Lipopolysaccharide rhamnose:kdoiii transferase; Lipopolysaccharide core biosynthesis; Protein involved in cell surface antigen activity, host-interacting and lipopolysaccharide core region biosynthetic process
      
 0.738
ygbN
Gluconate:h+ symporter, gntp family; Inner membrane permease YgbN; Putative transport protein
      
 0.732
malF
Maltose/maltodextrin transport system permease protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane
     
 0.515
ahpF
Alkyl hydroperoxide reductase, f52a subunit, fad/nad(p)-binding; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein
      
 0.505
bglF
Fused beta-glucoside-specific pts enzymes: iia component/iib component/iic component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport
 
   
 0.491
ebgR
Laci family transcriptional regulator, ebg operon repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer
  
     0.441
alsK
Catalyzes the phosphorylation of D-allose to D-allose 6- phosphate. Has also low level glucokinase activity in vitro
 
   
 0.439
nagE
N-acetyl glucosamine specific pts enzyme iic, iib, and iia components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . This system is involved in N-acetylglucosamine transport . It can also transport and phosphorylate the antibiotic streptozotocin . Could play a significant role in the recycling of peptidoglycan
     
 0.407
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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