STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dgoTMfs transporter, acs family, d-galactonate transporter; Intake of galactonate into the cell (430 aa)    
Predicted Functional Partners:
dgoK
2-dehydro-3-deoxygalactonokinase; Belongs to the DgoK family
 
   
 0.968
dgoD
D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate
 
 
 0.960
dgoA
2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- eryt [...]
 
  
 0.950
dgoR
Gntr family transcriptional regulator, galactonate operon transcriptional repressor; Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer
 
   
 0.943
yjiH
annotation not available
      
 0.790
kptA
Putative rna 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase
      
 0.737
ydiQ
Putative electron transfer flavoprotein subunit ydiq; May play a role in a redox process
      
 0.619
fucP
Mfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose
   
  
 0.619
gudD
D-glucarate dehydratase 1; Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D- glucarate (5-kdGluc). Also acts on L-idarate
 
 
 0.609
garD
D-galactarate dehydrogenase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate
 
    0.575
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.