node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
accC | ravA | b3256 | b3746 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.483 |
cadA | ldcC | b4131 | b0186 | Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide. Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation. Belongs to the Orn/Lys/Arg decarboxylase class-I family. | Lysine decarboxylase 2, constitutive; Plays a role in lysine utilization by acting as a lysine decarboxylase. | 0.959 |
cadA | ravA | b4131 | b3746 | Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide. Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation. Belongs to the Orn/Lys/Arg decarboxylase class-I family. | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.999 |
cadA | viaA | b4131 | b3745 | Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide. Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation. Belongs to the Orn/Lys/Arg decarboxylase class-I family. | Stimulator of RavA ATPase activity; von Willebrand factor domain protein. | 0.803 |
cadA | yaeR | b4131 | b0187 | Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide. Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation. Belongs to the Orn/Lys/Arg decarboxylase class-I family. | Putative lyase; To B.subtilis YwkD. | 0.808 |
frsA | ravA | b0239 | b3746 | Fermentation-respiration switch protein; Displays esterase activity toward pNP-butyrate. | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.519 |
frsA | viaA | b0239 | b3745 | Fermentation-respiration switch protein; Displays esterase activity toward pNP-butyrate. | Stimulator of RavA ATPase activity; von Willebrand factor domain protein. | 0.611 |
fucU | ravA | b2804 | b3746 | L-fucose mutarotase; Involved in the anomeric conversion of L-fucose. Catalyzes also the interconversion of beta-pyran and beta-furan forms of D- ribose; Belongs to the RbsD / FucU family. FucU mutarotase subfamily. | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.504 |
grpE | ravA | b2614 | b3746 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.544 |
kup | ravA | b3747 | b3746 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.648 |
kup | viaA | b3747 | b3745 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Stimulator of RavA ATPase activity; von Willebrand factor domain protein. | 0.499 |
ldcC | cadA | b0186 | b4131 | Lysine decarboxylase 2, constitutive; Plays a role in lysine utilization by acting as a lysine decarboxylase. | Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide. Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation. Belongs to the Orn/Lys/Arg decarboxylase class-I family. | 0.959 |
ldcC | ravA | b0186 | b3746 | Lysine decarboxylase 2, constitutive; Plays a role in lysine utilization by acting as a lysine decarboxylase. | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | 0.721 |
ldcC | yaeR | b0186 | b0187 | Lysine decarboxylase 2, constitutive; Plays a role in lysine utilization by acting as a lysine decarboxylase. | Putative lyase; To B.subtilis YwkD. | 0.871 |
ravA | accC | b3746 | b3256 | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.483 |
ravA | cadA | b3746 | b4131 | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide. Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation. Belongs to the Orn/Lys/Arg decarboxylase class-I family. | 0.999 |
ravA | frsA | b3746 | b0239 | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | Fermentation-respiration switch protein; Displays esterase activity toward pNP-butyrate. | 0.519 |
ravA | fucU | b3746 | b2804 | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | L-fucose mutarotase; Involved in the anomeric conversion of L-fucose. Catalyzes also the interconversion of beta-pyran and beta-furan forms of D- ribose; Belongs to the RbsD / FucU family. FucU mutarotase subfamily. | 0.504 |
ravA | grpE | b3746 | b2614 | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.544 |
ravA | kup | b3746 | b3747 | Hexameric AAA+ MoxR family ATPase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone. | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | 0.648 |