STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ravAHexameric aaa+ moxr family atpase, putative molecular chaperone; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (498 aa)    
Predicted Functional Partners:
cadA
Lysine decarboxylase, acid-inducible; Inducible lysine decarboxylase that catalyzes the proton- dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide . Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by- products of carbohydrate fermentation
    
 
 0.999
viaA
annotation not available
  
 0.998
ldcC
Lysine decarboxylase 2, constitutive; Plays a role in lysine utilization by acting as a lysine decarboxylase
    
 
 0.839
kup
Kup system potassium uptake protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium
     
 0.750
yjcS
Metallo-beta-lactamase superfamily protein; Belongs to the metallo-beta-lactamase superfamily
      
 0.734
fucU
L-fucose mutarotase; Involved in the anomeric conversion of L-fucose. Catalyzes also the interconversion of beta-pyran and beta-furan forms of D- ribose
    
   0.654
essQ
Prophage lysis protein S homolog EssQ; Phage or Prophage Related; Belongs to the lambda phage S protein family
      
 0.641
frsA
Fermentation-respiration switch protein; Displays esterase activity toward pNP-butyrate
  
    0.639
yrhB
Putative heat shock chaperone; Uncharacterized protein YrhB; Factor; Adaptations, atypical conditions
      
 0.603
dtpA
Proton-dependent oligopeptide transporter, pot family; Proton-dependent permease that transports di- and tripeptides as well as structurally related peptidomimetics such as aminocephalosporins into the cell. Has a clear preference for dipeptides and tripeptides composed of L-amino acids, and discriminates dipeptides on the basis of the position of charges within the substrate
      
 0.600
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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