node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
exuR | mcbR | b3094 | b1450 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | 0.479 |
exuR | rspR | b3094 | b1540 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | 0.681 |
exuR | uxuR | b3094 | b4324 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | 0.421 |
exuR | yieP | b3094 | b3755 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Putative transcriptional regulator. | 0.760 |
hsrA | yieP | b3754 | b3755 | Putative multidrug or homocysteine efflux system; Putative transport protein (MFS family); high copy suppressor of RspA: relieves RspA-mediated reduction of sigma(S) levels; overexpression also reduces MetE activity; effect proposed to be via an elevation in levels of homocysteine, causing a concomitant increase in homocysteine thiolactone; overexpression has no effect on resistance to a variety of toxic compounds; overexpression has no effect on resistance to a variety of toxic compounds; Belongs to the major facilitator superfamily. EmrB family. | Putative transcriptional regulator. | 0.790 |
mcbR | exuR | b1450 | b3094 | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | 0.479 |
mcbR | rspR | b1450 | b1540 | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | 0.767 |
mcbR | uxuR | b1450 | b4324 | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | 0.605 |
mcbR | yieP | b1450 | b3755 | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | Putative transcriptional regulator. | 0.705 |
rspR | exuR | b1540 | b3094 | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | 0.681 |
rspR | mcbR | b1540 | b1450 | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | 0.767 |
rspR | uxuR | b1540 | b4324 | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | 0.762 |
rspR | yieP | b1540 | b3755 | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | Putative transcriptional regulator. | 0.661 |
uxuR | exuR | b4324 | b3094 | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | 0.421 |
uxuR | mcbR | b4324 | b1450 | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy. | 0.605 |
uxuR | rspR | b4324 | b1540 | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | Transcriptional repressor for rspAB; Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA. | 0.762 |
uxuR | yieP | b4324 | b3755 | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | Putative transcriptional regulator. | 0.756 |
ybiH | ydcI | b0796 | b1422 | DUF1956 domain-containing tetR family putative transcriptional regulator; Regulates transcription of the cecR-ybhGFSR operon and the rhlE gene, which altogether are involved in the control of sensitivity to cefoperazone and chloramphenicol. Represses the cecR-ybhGFSR operon and activates the rhlE operon. Acts by binding to a palindromic sequence within the intergenic spacer located between these two divergently transcribed operons. | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | 0.511 |
ybiH | yiaJ | b0796 | b3574 | DUF1956 domain-containing tetR family putative transcriptional regulator; Regulates transcription of the cecR-ybhGFSR operon and the rhlE gene, which altogether are involved in the control of sensitivity to cefoperazone and chloramphenicol. Represses the cecR-ybhGFSR operon and activates the rhlE operon. Acts by binding to a palindromic sequence within the intergenic spacer located between these two divergently transcribed operons. | Transcriptional repressor for the yiaKLMNO-lyxK-sgbHUE operon; Negatively controls the transcription of the yiaKLMNOPQRS operon, which may be involved in the utilization of 2,3-diketo-L- gulonate. | 0.710 |
ybiH | yieP | b0796 | b3755 | DUF1956 domain-containing tetR family putative transcriptional regulator; Regulates transcription of the cecR-ybhGFSR operon and the rhlE gene, which altogether are involved in the control of sensitivity to cefoperazone and chloramphenicol. Represses the cecR-ybhGFSR operon and activates the rhlE operon. Acts by binding to a palindromic sequence within the intergenic spacer located between these two divergently transcribed operons. | Putative transcriptional regulator. | 0.694 |