node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hemG | pepQ | b3850 | b3847 | Protoporphyrin oxidase, flavoprotein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor. | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position and a polar or nonpolar amino acid at the N-terminal position. With much lower efficiency, also catalyzes the stereoselective hydrolysis of a wide variety of organophosphate triesters and organophosphonate diesters. Is able to hydrolyze the organophosphorus insecticide paraoxon and the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, Vx and rVX. | 0.695 |
hemG | trkH | b3850 | b3849 | Protoporphyrin oxidase, flavoprotein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor. | Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA. Requires TrkE (sapD) for transport activity, 20% more uptake is seen with both SapD and SapF. Transport in the absence of SapD and SapF is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins. Can transport potassium and rubidium. | 0.792 |
hemG | yigZ | b3850 | b3848 | Protoporphyrin oxidase, flavoprotein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor. | UPF0029 family protein; Protein involved in translation; Belongs to the IMPACT family. | 0.771 |
kch | kup | b1250 | b3747 | Voltage-gated potassium channel; K(+)-specific ion channel. May play a role in the defense against osmotic shock. | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | 0.582 |
kch | pfo | b1250 | b1378 | Voltage-gated potassium channel; K(+)-specific ion channel. May play a role in the defense against osmotic shock. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.466 |
kch | trkH | b1250 | b3849 | Voltage-gated potassium channel; K(+)-specific ion channel. May play a role in the defense against osmotic shock. | Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA. Requires TrkE (sapD) for transport activity, 20% more uptake is seen with both SapD and SapF. Transport in the absence of SapD and SapF is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins. Can transport potassium and rubidium. | 0.853 |
kdpA | kup | b0698 | b3747 | Potassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | 0.921 |
kdpA | sapD | b0698 | b1291 | Potassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Antimicrobial peptide ABC transporter ATPase; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. Stimulates K(+)-uptake proteins TrkG and TrkH to import K(+), may act via ATP-binding rather than ATP hydrolysis. | 0.540 |
kdpA | trkA | b0698 | b3290 | Potassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | NAD-binding component of TrK potassium transporter; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. | 0.566 |
kdpA | trkH | b0698 | b3849 | Potassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA. Requires TrkE (sapD) for transport activity, 20% more uptake is seen with both SapD and SapF. Transport in the absence of SapD and SapF is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins. Can transport potassium and rubidium. | 0.814 |
kup | kch | b3747 | b1250 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Voltage-gated potassium channel; K(+)-specific ion channel. May play a role in the defense against osmotic shock. | 0.582 |
kup | kdpA | b3747 | b0698 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Potassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. | 0.921 |
kup | sapD | b3747 | b1291 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Antimicrobial peptide ABC transporter ATPase; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. Stimulates K(+)-uptake proteins TrkG and TrkH to import K(+), may act via ATP-binding rather than ATP hydrolysis. | 0.600 |
kup | trkA | b3747 | b3290 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | NAD-binding component of TrK potassium transporter; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. | 0.897 |
kup | trkH | b3747 | b3849 | Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA. Requires TrkE (sapD) for transport activity, 20% more uptake is seen with both SapD and SapF. Transport in the absence of SapD and SapF is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins. Can transport potassium and rubidium. | 0.915 |
pepQ | hemG | b3847 | b3850 | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position and a polar or nonpolar amino acid at the N-terminal position. With much lower efficiency, also catalyzes the stereoselective hydrolysis of a wide variety of organophosphate triesters and organophosphonate diesters. Is able to hydrolyze the organophosphorus insecticide paraoxon and the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, Vx and rVX. | Protoporphyrin oxidase, flavoprotein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor. | 0.695 |
pepQ | pfo | b3847 | b1378 | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position and a polar or nonpolar amino acid at the N-terminal position. With much lower efficiency, also catalyzes the stereoselective hydrolysis of a wide variety of organophosphate triesters and organophosphonate diesters. Is able to hydrolyze the organophosphorus insecticide paraoxon and the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, Vx and rVX. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.456 |
pepQ | trkH | b3847 | b3849 | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position and a polar or nonpolar amino acid at the N-terminal position. With much lower efficiency, also catalyzes the stereoselective hydrolysis of a wide variety of organophosphate triesters and organophosphonate diesters. Is able to hydrolyze the organophosphorus insecticide paraoxon and the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, Vx and rVX. | Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA. Requires TrkE (sapD) for transport activity, 20% more uptake is seen with both SapD and SapF. Transport in the absence of SapD and SapF is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins. Can transport potassium and rubidium. | 0.751 |
pepQ | yigZ | b3847 | b3848 | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position and a polar or nonpolar amino acid at the N-terminal position. With much lower efficiency, also catalyzes the stereoselective hydrolysis of a wide variety of organophosphate triesters and organophosphonate diesters. Is able to hydrolyze the organophosphorus insecticide paraoxon and the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, Vx and rVX. | UPF0029 family protein; Protein involved in translation; Belongs to the IMPACT family. | 0.928 |
pfo | kch | b1378 | b1250 | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | Voltage-gated potassium channel; K(+)-specific ion channel. May play a role in the defense against osmotic shock. | 0.466 |