STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frvRPutative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. (582 aa)    
Predicted Functional Partners:
frvX
Putative peptidase; Frv operon protein; Protein involved in polysaccharide catabolic process.
 
    0.973
frvB
Putative PTS enzyme, IIB component/IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrvAB PTS system is involved in fructose transport.
 
  
 0.936
mtlA
Mannitol-specific PTS enzyme: IIA, IIB and IIC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in D-mannitol transport. Also able to use D-mannonic acid.
  
  
 0.888
frvA
Putative enzyme IIA component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrvAB PTS system is involved in fructose transport.
 
  
 0.851
yhcA
Putative periplasmic chaperone protein; Could be required for the biogenesis of a putative fimbria. Belongs to the periplasmic pilus chaperone family.
   
  
 0.804
waaL
O-antigen ligase; Adds the O-antigen on the glucose group of LPS.
  
     0.774
waaU
Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS.
  
     0.773
yqcE
Putative MFS transporter, inner membrane protein; Putative transport protein.
  
     0.766
ygfI
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
  
     0.732
yghQ
Putative inner membrane polysaccharide flippase.
  
  
 0.727
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.