STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
rhaTL-rhamnose-h+ transport protein; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-mannose and L-xylose, but at reduced rates (344 aa)    
Predicted Functional Partners:
Arac family transcriptional regulator, l-rhamnose operon transcriptional activator rhar; Activates expression of the rhaSR operon in response to L- rhamnose
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). It could also play a role in the metabolism of some rare sugars such as L-fructose. Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1- phosphate. Uridine triphosphate (UTP), cytidine 5-triphosphate (CTP), guanosine 5-triphosphate (GTP), and thymidine triphosphate (TTP) also can act as phosphoryl donors. It can also phosphorylate L-fuculose and L-xylulose
Arac family transcriptional regulator, l-rhamnose operon regulatory protein rhas; Activates expression of the rhaBAD and rhaT operons
L-rhamnose isomerase; Protein involved in carbohydrate catabolic process
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde . Also catalyzes the dephosphorylation of phospho- serine in vitro
L-rhamnose mutarotase; Involved in the anomeric conversion of L-rhamnose
Arac family transcriptional regulator, arabinose operon regulatory protein; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose Functions both as a positive and a negative regulator . In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters In the absence of arabinose, negatively regulates the araBAD operon . Represses its own transcription . Acts by binding directly to DNA
Cysteine and o-acetyl-l-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites
Superoxide dismutase, fe-mn family; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems
Mfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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