STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yiiMannotation not available (224 aa)    
Predicted Functional Partners:
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family
   
 0.905
yeaX
Carnitine monooxygenase reductase subunit; Converts carnitine to trimethylamine and malic semialdehyde. Can also use gamma-butyrobetaine, choline and betaine as substrates; Belongs to the PDR/VanB family. CntB subfamily
    
 0.876
yfaD
Inactive recombination-promoting nuclease-like protein RpnE; Upon expression has no effect on RecA-independent DNA recombination, cell viability or DNA damage
      
 0.809
agaS
Putative D-galactosamine-6-phosphate deaminase AgaS; Catalyzes the isomerization-deamination of galactosamine 6-phosphate to form tagatofuranose 6-phosphate and ammonium ion
      
 0.752
nemR
HTH-type transcriptional repressor NemR; Represses the transcription of the nemRA operon by binding to the nemR box
      
 0.680
hcr
NADH oxidoreductase HCR; NADH oxidoreductase acting in concert with HCP
   
 0.559
yhfT
Uncharacterized protein YhfT; Putative transport system permease protein
  
   
 0.530
kdgT
2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
       0.511
glnL
Sensory histidine kinase/phosphatase NtrB; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC. In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC
     
 0.501
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template
     
 0.474
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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