STRINGSTRING
malK protein (Escherichia coli K12 MG1655) - STRING interaction network
"malK" - Maltose/maltodextrin import ATP-binding protein MalK in Escherichia coli K12 MG1655
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malKMaltose/maltodextrin import ATP-binding protein MalK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family (371 aa)    
Predicted Functional Partners:
malF
Maltose transport system permease protein MalF; Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane (514 aa)
 
  0.999
malG
Maltose transport system permease protein MalG; Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane (296 aa)
 
  0.999
malE
Maltose-binding periplasmic protein; Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides; Belongs to the bacterial solute-binding protein 1 family (396 aa)
 
  0.999
lamB
Maltoporin; Involved in the transport of maltose and maltodextrins, indispensable for translocation of dextrins containing more than three glucosyl moieties. A hydrophobic path ("greasy slide") of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda (446 aa)
 
   
  0.998
malM
Maltose operon periplasmic protein; Not yet known. Might function in the uptake of a still unidentified substrate (306 aa)
 
   
  0.995
malT
HTH-type transcriptional regulator MalT; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box)- 5’-GGA[TG]GA-3’ (901 aa)
   
 
  0.982
ugpE
Sn-glycerol-3-phosphate transport system permease protein UgpE; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane (281 aa)
  0.961
ugpA
Sn-glycerol-3-phosphate transport system permease protein UgpA; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane (295 aa)
  0.960
potC
Spermidine/putrescine transport system permease protein PotC; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine (264 aa)
 
  0.924
rbsA
Ribose import ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family (501 aa)
   
   
0.915
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (20%) [HD]