STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltPGlutamate/aspartate : h(+) symporter gltp; Catalyzes the proton-dependent, binding-protein-independent transport of glutamate and aspartate (437 aa)    
Predicted Functional Partners:
gltS
Glutamate:na+ symporter, ess family; Catalyzes the sodium-dependent, binding-protein-independent transport of glutamate
      
 0.872
yjcO
annotation not available
      
 0.732
yqcE
Putative mfs transporter, inner membrane protein; Inner membrane protein YqcE; Putative transport protein
     
 0.678
nrfE
Heme lyase (nrfefg) for insertion of heme into c552, subunit nrfe; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase
     
 0.606
yijD
annotation not available
      
 0.561
nrfF
Heme lyase (nrfefg) for insertion of heme into c552, subunit nrff; Not required for the biosynthesis of any of the c-type cytochromes. Possible subunit of a heme lyase
     
 0.559
evgS
Hybrid sensory histidine kinase in two-component regulatory system with evga; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals
  
  
 0.550
brnQ
Branched-chain amino acid transport system 2 carrier protein; Component of the LIV-II transport system for branched-chain amino acids. This LIV-II transport system may be H(+)-coupled
  
   
 0.544
yiaO
2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L- gulonate. This protein specifically binds 2,3-diketo-L-gulonate. Is not able to bind either L-ascorbate or dehydroascorbate
     
 0.538
proY
Proline-specific permease proy; Permease that is involved in the transport across the cytoplasmic membrane of proline
      
 0.525
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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