STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
alsRD-allose-inducible als operon transcriptional repressor; Regulatory protein involved in rpiB gene repression. Also involved in als operon repression. (296 aa)    
Predicted Functional Partners:
alsC
D-allose ABC transporter permease; Part of the binding-protein-dependent transport system AlsBAC for D-allose; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
  
  
 0.948
rpiB
Ribose 5-phosphate isomerase B/allose 6-phosphate isomerase; Catalyzes the interconversion of ribulose-5-P and ribose-5-P. It probably also has activity on D-allose 6-phosphate.
  
  
 0.947
alsB
D-allose ABC transporter periplasmic binding protein; Part of the binding-protein-dependent transport system AlsBAC for D-allose; Belongs to the bacterial solute-binding protein 2 family.
  
    0.946
glk
Glucokinase; Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
    
 0.889
alsA
D-allose ABC transporter ATPase; Part of the ABC transporter complex AlsBAC involved in D- allose import. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. D-allose importer (TC 3.A.1.2.6) family.
  
  
 0.878
alsE
Allulose-6-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-allulose 6- phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D- xylulose 5-phosphate.
  
  
 0.877
alsK
D-allose kinase; Catalyzes the phosphorylation of D-allose to D-allose 6- phosphate. Has also low level glucokinase activity in vitro. Belongs to the ROK (NagC/XylR) family.
  
  
 0.856
lacI
Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer.
   
  
 0.659
murQ
N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Is required for growth on MurNAc as the sole source of carbon and energy. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
 
  
 0.647
deoR
Deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes. It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore-forming protein). The inducer is deoxyribose-5-phosphate.
      
 0.645
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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