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phnG protein (Escherichia coli K12 MG1655) - STRING interaction network
"phnG" - Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG in Escherichia coli K12 MG1655
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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phnGAlpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate (150 aa)    
Predicted Functional Partners:
phnH
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH; Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate (194 aa)
 
  0.999
phnI
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI; Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively (354 aa)
 
  0.999
phnJ
Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2- cyclic phosphate 5-phosphate (PRcP) (281 aa)
 
  0.999
phnK
Putative phosphonates utilization ATP-binding protein PhnK; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction (252 aa)
 
  0.999
phnM
Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase; Catalyzes the hydrolysis of alpha-D-ribose 1- methylphosphonate triphosphate (RPnTP) to form alpha-D-ribose 1- methylphosphonate phosphate (PRPn) and diphosphate; Belongs to the metallo-dependent hydrolases superfamily (378 aa)
 
 
  0.999
phnL
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL; Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate (226 aa)
 
 
  0.999
phnF
Probable transcriptional regulator PhnF; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator (241 aa)
 
   
  0.998
phnN
Ribose 1,5-bisphosphate phosphokinase PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor (185 aa)
 
   
  0.994
phnP
Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase; Catalyzes the hydrolysis of the cyclic ribose-phosphate to form alpha-D-ribose 1,5-bisphosphate (252 aa)
 
   
  0.992
phnC
Phosphonates import ATP-binding protein PhnC; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system (262 aa)
 
   
  0.971
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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