node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
phnC | phnD | b4106 | b4105 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | 0.999 |
phnC | phnF | b4106 | b4102 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Putative dna-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator | 0.975 |
phnC | phnG | b4106 | b4101 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phng; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate | 0.985 |
phnC | phnH | b4106 | b4100 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phnh; Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate | 0.986 |
phnC | phnI | b4106 | b4099 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phni; Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively | 0.984 |
phnC | phnJ | b4106 | b4098 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Alpha-d-ribose 1-methylphosphonate 5-phosphate c-p lyase; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP) | 0.987 |
phnC | phnK | b4106 | b4097 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Carbon-phosphorus lyase complex subunit, putative atp transporter atp-binding protein; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction | 0.712 |
phnC | phnL | b4106 | b4096 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phnl; Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate | 0.649 |
phnC | phnM | b4106 | b4095 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Alpha-d-ribose 1-methylphosphonate 5-triphosphate diphosphatase; Catalyzes the hydrolysis of alpha-D-ribose 1- methylphosphonate triphosphate (RPnTP) to form alpha-D-ribose 1- methylphosphonate phosphate (PRPn) and diphosphate | 0.983 |
phnC | phnN | b4106 | b4094 | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | Ribose 1,5-bisphosphate phosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor | 0.974 |
phnD | phnC | b4105 | b4106 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Phosphonate transport system atp-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system | 0.999 |
phnD | phnF | b4105 | b4102 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Putative dna-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator | 0.982 |
phnD | phnG | b4105 | b4101 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phng; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate | 0.988 |
phnD | phnH | b4105 | b4100 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phnh; Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate | 0.988 |
phnD | phnI | b4105 | b4099 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phni; Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively | 0.988 |
phnD | phnJ | b4105 | b4098 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Alpha-d-ribose 1-methylphosphonate 5-phosphate c-p lyase; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP) | 0.990 |
phnD | phnK | b4105 | b4097 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Carbon-phosphorus lyase complex subunit, putative atp transporter atp-binding protein; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction | 0.988 |
phnD | phnL | b4105 | b4096 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Alpha-d-ribose 1-methylphosphonate 5-triphosphate synthase subunit phnl; Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate | 0.986 |
phnD | phnM | b4105 | b4095 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Alpha-d-ribose 1-methylphosphonate 5-triphosphate diphosphatase; Catalyzes the hydrolysis of alpha-D-ribose 1- methylphosphonate triphosphate (RPnTP) to form alpha-D-ribose 1- methylphosphonate phosphate (PRPn) and diphosphate | 0.987 |
phnD | phnN | b4105 | b4094 | Phosphonate abc transporter periplasmic binding protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate | Ribose 1,5-bisphosphate phosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor | 0.981 |