Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crr | glpK | b2417 | b3926 | Glucose-specific enzyme iia component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II complex composed of PtsG and Crr is involved in glucose transport . The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an [...] | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP | 0.999 |
| crr | lacY | b2417 | b0343 | Glucose-specific enzyme iia component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II complex composed of PtsG and Crr is involved in glucose transport . The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an [...] | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | 0.890 |
| crr | melB | b2417 | b4120 | Glucose-specific enzyme iia component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II complex composed of PtsG and Crr is involved in glucose transport . The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an [...] | Melibiose:h(+)/na(+)/li(+) symporter; Responsible for melibiose and other galactoside transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system) | 0.739 |
| fucP | lacY | b2801 | b0343 | Mfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | 0.889 |
| fucP | melB | b2801 | b4120 | Mfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose | Melibiose:h(+)/na(+)/li(+) symporter; Responsible for melibiose and other galactoside transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system) | 0.572 |
| fucP | xylE | b2801 | b4031 | Mfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose | Mfs transporter, sp family, xylose:h+ symportor; Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Glucose is not transported, but can compete for xylose binding sites and can inhibit xylose transport (in vitro) | 0.895 |
| glpK | crr | b3926 | b2417 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP | Glucose-specific enzyme iia component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II complex composed of PtsG and Crr is involved in glucose transport . The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an [...] | 0.999 |
| glpK | lacY | b3926 | b0343 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | 0.426 |
| glpK | melB | b3926 | b4120 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP | Melibiose:h(+)/na(+)/li(+) symporter; Responsible for melibiose and other galactoside transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system) | 0.562 |
| hdhA | melB | b1619 | b4120 | 7-alpha-hydroxysteroid dehydrogenase, NAD-dependent; Catalyzes the oxidation of the 7-alpha-hydroxy group of primary bile acids such as cholate, chenodeoxycholate and taurochenodeoxycholate . To a lesser extent, also able to use taurocholate and glycocholate | Melibiose:h(+)/na(+)/li(+) symporter; Responsible for melibiose and other galactoside transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system) | 0.588 |
| lacY | crr | b0343 | b2417 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Glucose-specific enzyme iia component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II complex composed of PtsG and Crr is involved in glucose transport . The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an [...] | 0.890 |
| lacY | fucP | b0343 | b2801 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Mfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose | 0.889 |
| lacY | glpK | b0343 | b3926 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP | 0.426 |
| lacY | melA | b0343 | b4119 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Alpha-galactosidase, nad(p)-binding; Belongs to the glycosyl hydrolase 4 family | 0.520 |
| lacY | melB | b0343 | b4120 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Melibiose:h(+)/na(+)/li(+) symporter; Responsible for melibiose and other galactoside transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system) | 0.905 |
| lacY | nhaA | b0343 | b0019 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Na+:h+ antiporter, nhaa family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5 | 0.613 |
| lacY | xylE | b0343 | b4031 | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | Mfs transporter, sp family, xylose:h+ symportor; Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Glucose is not transported, but can compete for xylose binding sites and can inhibit xylose transport (in vitro) | 0.879 |
| melA | lacY | b4119 | b0343 | Alpha-galactosidase, nad(p)-binding; Belongs to the glycosyl hydrolase 4 family | Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate | 0.520 |
| melA | melB | b4119 | b4120 | Alpha-galactosidase, nad(p)-binding; Belongs to the glycosyl hydrolase 4 family | Melibiose:h(+)/na(+)/li(+) symporter; Responsible for melibiose and other galactoside transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system) | 0.988 |
| melA | melR | b4119 | b4118 | Alpha-galactosidase, nad(p)-binding; Belongs to the glycosyl hydrolase 4 family | Arac family transcriptional regulator, melibiose operon regulatory protein; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site | 0.966 |
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