node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ansB | aspA | b2957 | b4139 | Periplasmic l-asparaginase 2; Belongs to the asparaginase 1 family | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | 0.988 |
ansB | dcuA | b2957 | b4138 | Periplasmic l-asparaginase 2; Belongs to the asparaginase 1 family | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | 0.563 |
aspA | ansB | b4139 | b2957 | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | Periplasmic l-asparaginase 2; Belongs to the asparaginase 1 family | 0.988 |
aspA | cutA | b4139 | b4137 | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | 0.463 |
aspA | dcuA | b4139 | b4138 | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | 0.831 |
aspA | yjdC | b4139 | b4135 | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | Putative dna-binding transcriptional regulator yjdc; HTH-type transcriptional regulator YjdC; Anticodon: GAA | 0.441 |
cutA | aspA | b4137 | b4139 | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | 0.463 |
cutA | dcuA | b4137 | b4138 | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | 0.594 |
cutA | dsbD | b4137 | b4136 | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | Thiol:disulfide interchange protein and activator of dsbc; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps | 0.989 |
cutA | sugE | b4137 | b4148 | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | Quaternary ammonium compound-resistance protein suge; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons . Overexpression leads to resistance to a subset of toxic quaternary ammonium compounds such as cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations | 0.482 |
cutA | yjdC | b4137 | b4135 | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | Putative dna-binding transcriptional regulator yjdc; HTH-type transcriptional regulator YjdC; Anticodon: GAA | 0.837 |
dcuA | ansB | b4138 | b2957 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Periplasmic l-asparaginase 2; Belongs to the asparaginase 1 family | 0.563 |
dcuA | aspA | b4138 | b4139 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Aspartate ammonia-lyase (aspartase); Protein involved in cellular amino acid metabolic process, asparagine biosynthetic process and lysine biosynthetic process via diaminopimelate | 0.831 |
dcuA | cutA | b4138 | b4137 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Divalent-cation tolerance protein, copper sensitivity; Involved in resistance toward heavy metals | 0.594 |
dcuA | dhaR | b4138 | b1201 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | 0.781 |
dcuA | dsbD | b4138 | b4136 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Thiol:disulfide interchange protein and activator of dsbc; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps | 0.581 |
dcuA | hyaB | b4138 | b0973 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Hydrogenase 1, large subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth | 0.638 |
dcuA | sugE | b4138 | b4148 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Quaternary ammonium compound-resistance protein suge; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons . Overexpression leads to resistance to a subset of toxic quaternary ammonium compounds such as cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations | 0.627 |
dcuA | ubiI | b4138 | b2906 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | 2-octaprenylphenol hydroxylase, FAD-dependent; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis | 0.733 |
dcuA | yidE | b4138 | b3685 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Putative transport protein yide; Putative transport protein | 0.574 |