node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bdcA | bdcR | b4249 | b4251 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | 0.929 |
bdcA | mhpA | b4249 | b0347 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). | 0.465 |
bdcA | nuoC | b4249 | b2286 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | NADH:ubiquinone oxidoreductase, fused CD subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.718 |
bdcA | tabA | b4249 | b4252 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Biofilm modulator regulated by toxins; Influences biofilm formation. Represses fimbria genes in 8 hours biofilms. May act in response to the combined activity of several toxin-antitoxin (TA) systems. | 0.553 |
bdcA | ucpA | b4249 | b2426 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Furfural resistance protein, putative short-chain oxidoreductase; Putative oxidoreductase. | 0.540 |
bdcA | yciK | b4249 | b1271 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Putative EmrKY-TolC system oxoacyl-(acyl carrier protein) reductase; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.495 |
bdcA | ygfF | b4249 | b2902 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Putative oxidoreductase. | 0.590 |
bdcA | yidJ | b4249 | b3678 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Sulfatase/phosphatase superfamily protein; Putative sulfatase; Protein involved in sulfur metabolic process; Belongs to the sulfatase family. | 0.522 |
bdcA | yjgH | b4249 | b4248 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | UPF0131 family protein; Protein involved in translation. | 0.792 |
bdcA | ytfT | b4249 | b4230 | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | Putative sugar ABC transporter permease; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. | 0.455 |
bdcR | bdcA | b4251 | b4249 | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | 0.929 |
bdcR | mhpA | b4251 | b0347 | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). | 0.811 |
bdcR | tabA | b4251 | b4252 | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | Biofilm modulator regulated by toxins; Influences biofilm formation. Represses fimbria genes in 8 hours biofilms. May act in response to the combined activity of several toxin-antitoxin (TA) systems. | 0.482 |
bdcR | yjgH | b4251 | b4248 | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | UPF0131 family protein; Protein involved in translation. | 0.847 |
bdcR | ytfT | b4251 | b4230 | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | Putative sugar ABC transporter permease; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. | 0.604 |
mhpA | bdcA | b0347 | b4249 | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | 0.465 |
mhpA | bdcR | b0347 | b4251 | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). | Transcriptional repressor for divergent bdcA; Negatively regulates expression of bdcA. | 0.811 |
mhpA | ytfT | b0347 | b4230 | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). | Putative sugar ABC transporter permease; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. | 0.522 |
nuoC | bdcA | b2286 | b4249 | NADH:ubiquinone oxidoreductase, fused CD subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | c-di-GMP-binding biofilm dispersal mediator protein; Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase. | 0.718 |
nuoC | ucpA | b2286 | b2426 | NADH:ubiquinone oxidoreductase, fused CD subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | Furfural resistance protein, putative short-chain oxidoreductase; Putative oxidoreductase. | 0.718 |