STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjgNannotation not available (398 aa)    
Predicted Functional Partners:
yfjP
Uncharacterized protein YfjP; Putative GTP-binding protein; To E.coli YkfA and YeeP
      
 0.920
yibG
Uncharacterized protein YibG; Rhs-family protein
   
  
 0.843
yieP
annotation not available
      
 0.835
yhdZ
Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ; Probably part of a binding-protein-dependent transport system YdhWXYZ for an amino acid. Probably responsible for energy coupling to the transport system
      
 0.830
yigL
Pyridoxal phosphate phosphatase YigL; Catalyzes Strongly the dephosphorylation of pyridoxal- phosphate (PLP) and moderately the dephosphorylation of 2- deoxyglucose 6-phosphate (2bGLU6P) and beta-glucose 6-phosphate (bGlu6P). Also hydrolyzes both purines (GMP and IMP) and pyrimidines as secondary substrates
      
 0.810
alx
Putative membrane-bound redox modulator Alx; Has been proposed to be a redox modulator
      
 0.770
ppiC
Peptidyl-prolyl cis-trans isomerase C; PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates; Belongs to the PpiC/parvulin rotamase family
      
 0.754
glnD
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins GlnB and GlnK, in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism
      
 0.753
yrhB
Uncharacterized protein YrhB; Factor; Adaptations, atypical conditions
      
 0.750
ybeR
annotation not available
  
     0.709
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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