STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
osmYHyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress (201 aa)    
Predicted Functional Partners:
osmC
Peroxiredoxin OsmC; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family
   
  
 0.907
ybaY
Uncharacterized lipoprotein YbaY; Glycoprotein/polysaccharide metabolism; Protein involved in lipoprotein biosynthetic process and glycoprotein biosynthetic process
  
   0.837
osmE
Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress
   
 
 0.829
elaB
annotation not available
 
    0.827
yqjD
Uncharacterized protein YqjD; Upon overexpression inhibits growth
 
    0.825
msyB
Acidic protein MsyB; Could participate in the normal pathway of protein export
  
    0.815
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
   
    0.810
yqjC
annotation not available
  
    0.799
otsA
Trehalose-6-phosphate synthase; Catalyzes the transfer of glucose from UDP-glucose (UDP- Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6- phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength; Belongs to the glycosyltransferase 20 family
  
  
 0.793
yeaG
annotation not available
   
  
 0.792
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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