STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
creDInner membrane protein CreD; Tolerance to colicin E2 (450 aa)    
Predicted Functional Partners:
creC
Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB.
 
  
 0.993
creB
Member of the two-component regulatory system CreC/CreB involved in catabolic regulation
 
  
 0.980
creA
annotation not available
     
 0.936
dacB
Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction.
      
 0.748
blr
Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions
      
 0.731
ampD
Involved in cell wall peptidoglycan recycling . Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety . Is also involved in beta-lactamase induction
      
 0.673
cbrA
Belongs to the CbrA family
  
  
 0.597
dcrB
Required for phage C1 adsorption
      
 0.568
ynbC
annotation not available
  
     0.557
ycaC
Probable hydrolase YcaC; Protein involved in cellular amino acid catabolic process
      
 0.553
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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