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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfjDUPF0053 inner membrane protein YfjD; Putative membrane protein (428 aa)    
Predicted Functional Partners:
ypjD
annotation not available
  
    0.850
ffh
Signal recognition particle (srp) component with 4.5s rna (ffs); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex [...]
  
    0.717
ybeR
DUF1266 domain-containing protein YbeR; To E.coli YbeU
      
 0.702
yehP
annotation not available
      
 0.654
ynfA
annotation not available
 
   
 0.648
yfaT
DUF1175 domain-containing protein YfaT; To P.aeruginosa PA4490 and T.maritima TM0986
      
 0.618
actP
Acetate/glycolate:cation symporter; Transports acetate. Also able to transport glycolate
      
 0.608
hiuH
Hydroxyisourate hydrolase/transthyretin-related protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU)
      
 0.607
yicL
Eama family inner membrane putative transporter; Uncharacterized inner membrane transporter YicL; Putative permease transporter
      
 0.603
yniB
annotation not available
      
 0.602
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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