node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eda | edd | b1850 | b1851 | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | 0.999 |
eda | gntK | b1850 | b3437 | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | 0.775 |
eda | gntR | b1850 | b3438 | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | 0.457 |
eda | gntU | b1850 | b4476 | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | Gluconate transporter, low affinity GNT 1 system; Part of the gluconate utilization system Gnt-I; low-affinity intake of gluconate; Belongs to the GntP permease family. | 0.537 |
eda | idnK | b1850 | b4268 | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | D-gluconate kinase, thermosensitive; Protein involved in carbohydrate catabolic process; Belongs to the gluconokinase GntK/GntV family. | 0.611 |
edd | eda | b1851 | b1850 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | 0.999 |
edd | gntK | b1851 | b3437 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | 0.977 |
edd | gntR | b1851 | b3438 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | 0.629 |
edd | gntU | b1851 | b4476 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | Gluconate transporter, low affinity GNT 1 system; Part of the gluconate utilization system Gnt-I; low-affinity intake of gluconate; Belongs to the GntP permease family. | 0.646 |
edd | idnK | b1851 | b4268 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | D-gluconate kinase, thermosensitive; Protein involved in carbohydrate catabolic process; Belongs to the gluconokinase GntK/GntV family. | 0.969 |
edd | idnR | b1851 | b4264 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | Transcriptional repressor, 5-gluconate-binding; Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate. | 0.453 |
gntK | eda | b3437 | b1850 | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | 0.775 |
gntK | edd | b3437 | b1851 | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | 0.977 |
gntK | gntR | b3437 | b3438 | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | 0.878 |
gntK | gntU | b3437 | b4476 | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | Gluconate transporter, low affinity GNT 1 system; Part of the gluconate utilization system Gnt-I; low-affinity intake of gluconate; Belongs to the GntP permease family. | 0.970 |
gntK | idnK | b3437 | b4268 | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | D-gluconate kinase, thermosensitive; Protein involved in carbohydrate catabolic process; Belongs to the gluconokinase GntK/GntV family. | 0.910 |
gntR | eda | b3438 | b1850 | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | KHG/KDPG aldolase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) to pyruvate and D- glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with si-facial selectivity. It accepts some nucleophiles other than pyruvate, including 2-oxobutanoate, phenylpyruvate, and fluorobutanoate. It has a preference for the S-configuration at C2 of the electrophile. | 0.457 |
gntR | edd | b3438 | b1851 | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate. | 0.629 |
gntR | gntK | b3438 | b3437 | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | Gluconokinase 2, thermoresistant; gluconate transport, GNT I system; Protein involved in glucose metabolic process; Belongs to the gluconokinase GntK/GntV family. | 0.878 |
gntR | gntU | b3438 | b4476 | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | Gluconate transporter, low affinity GNT 1 system; Part of the gluconate utilization system Gnt-I; low-affinity intake of gluconate; Belongs to the GntP permease family. | 0.799 |