STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rzoDComponent of the spanin complex that disrupts the outer membrane and causes cell lysis during virus exit. The spanin complex conducts the final step in cell lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans (By similarity) (60 aa)    
Predicted Functional Partners:
essD
Prophage lysis protein S homolog EssD; Phage or Prophage Related
      
 0.882
quuD
Positively regulate expression of some phage genes. Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity)
      
 0.878
rzpD
Necessary for host cell lysis. It is believed to code for an endopeptidase that cleaves the amino-carboxyl cross-link between the diaminopimelic acid and D-alanine residues in the murein component of the bacterial cell wall (By similarity)
      
 0.877
ybfD
Belongs to the transposase 11 family
      
 0.874
pinQ
Serine recombinase PinQ; Phage or Prophage Related; Belongs to the site-specific recombinase resolvase family
      
 0.874
tfaQ
Belongs to the tfa family
      
 0.873
ydfK
Cold shock protein YdfK; Cryptic prophage Qin/Kim
      
 0.872
ynaE
Uncharacterized protein YnaE; Phage or Prophage Related
      
 0.871
tfaR
Belongs to the tfa family
      
 0.870
pinR
Serine recombinase PinR; Phage or Prophage Related
      
 0.824
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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