node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bluR | nac | b1162 | b1988 | Repressor of blue light-responsive genes; Controls the expression of several small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon and also regulates ynaK. Binding is antagonized by BluF upon blue light (470 nm) irradiation. Blue light may increase the affinity of BluF for BluR, allowing it to be released from its operator. | Nitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). | 0.527 |
bluR | ybdD | b1162 | b4512 | Repressor of blue light-responsive genes; Controls the expression of several small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon and also regulates ynaK. Binding is antagonized by BluF upon blue light (470 nm) irradiation. Blue light may increase the affinity of BluF for BluR, allowing it to be released from its operator. | DUF466 family protein; To E.coli YjiX. | 0.544 |
bluR | yphA | b1162 | b2543 | Repressor of blue light-responsive genes; Controls the expression of several small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon and also regulates ynaK. Binding is antagonized by BluF upon blue light (470 nm) irradiation. Blue light may increase the affinity of BluF for BluR, allowing it to be released from its operator. | DoxX family inner membrane protein. | 0.453 |
cstA | ybdD | b0598 | b4512 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | DUF466 family protein; To E.coli YjiX. | 0.937 |
mhpD | ybdD | b0350 | b4512 | 2-keto-4-pentenoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily. | DUF466 family protein; To E.coli YjiX. | 0.600 |
nac | bluR | b1988 | b1162 | Nitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). | Repressor of blue light-responsive genes; Controls the expression of several small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon and also regulates ynaK. Binding is antagonized by BluF upon blue light (470 nm) irradiation. Blue light may increase the affinity of BluF for BluR, allowing it to be released from its operator. | 0.527 |
nac | ybdD | b1988 | b4512 | Nitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). | DUF466 family protein; To E.coli YjiX. | 0.730 |
nac | yohC | b1988 | b2135 | Nitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). | Yip1 family inner membrane protein. | 0.457 |
nac | yphA | b1988 | b2543 | Nitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). | DoxX family inner membrane protein. | 0.529 |
ybdD | bluR | b4512 | b1162 | DUF466 family protein; To E.coli YjiX. | Repressor of blue light-responsive genes; Controls the expression of several small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon and also regulates ynaK. Binding is antagonized by BluF upon blue light (470 nm) irradiation. Blue light may increase the affinity of BluF for BluR, allowing it to be released from its operator. | 0.544 |
ybdD | cstA | b4512 | b0598 | DUF466 family protein; To E.coli YjiX. | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | 0.937 |
ybdD | mhpD | b4512 | b0350 | DUF466 family protein; To E.coli YjiX. | 2-keto-4-pentenoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily. | 0.600 |
ybdD | nac | b4512 | b1988 | DUF466 family protein; To E.coli YjiX. | Nitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). | 0.730 |
ybdD | yhjG | b4512 | b3524 | DUF466 family protein; To E.coli YjiX. | Putative inner membrane-anchored periplasmic AsmA family protein. | 0.560 |
ybdD | yjiY | b4512 | b4354 | DUF466 family protein; To E.coli YjiX. | Putative transporter; Transports pyruvate with a high affinity and specificity. The process is driven by the proton motive force. Part of a nutrient-sensing regulatory network composed of the two-component regulatory systems BtsS/BtsR and YpdA/YpdB, and their respective target proteins, BtsT and YhjX. Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family. | 0.908 |
ybdD | yohC | b4512 | b2135 | DUF466 family protein; To E.coli YjiX. | Yip1 family inner membrane protein. | 0.620 |
ybdD | ypdA | b4512 | b2380 | DUF466 family protein; To E.coli YjiX. | Sensor kinase regulating yhjX; Member of the two-component regulatory system YpdA/YpdB, which is part of a nutrient-sensing regulatory network composed of YpdA/YpdB, the high-affinity pyruvate signaling system BtsS/BtsR and their respective target proteins, YhjX and BtsT. YpdA activates YpdB by phosphorylation in response to high concentrations of extracellular pyruvate. Activation of the YpdA/YpdB signaling cascade also promotes BtsS/BtsR-mediated btsT expression. | 0.532 |
ybdD | ypdB | b4512 | b2381 | DUF466 family protein; To E.coli YjiX. | Response regulator activating yhjX; Member of the two-component regulatory system YpdA/YpdB, which is part of a nutrient-sensing regulatory network composed of YpdA/YpdB, the high-affinity pyruvate signaling system BtsS/BtsR and their respective target proteins, YhjX and BtsT. YpdB regulates expression of yhjX by binding to its promoter region. Activation of the YpdA/YpdB signaling cascade also promotes BtsS/BtsR-mediated btsT expression. | 0.533 |
ybdD | yphA | b4512 | b2543 | DUF466 family protein; To E.coli YjiX. | DoxX family inner membrane protein. | 0.775 |
yhjG | ybdD | b3524 | b4512 | Putative inner membrane-anchored periplasmic AsmA family protein. | DUF466 family protein; To E.coli YjiX. | 0.560 |