STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cydXCytochrome d (bd-i) ubiquinol oxidase subunit x; Required for correct functioning of cytochrome bd-I oxidase. This protein and AppX may have some functional overlap (37 aa)    
Predicted Functional Partners:
cydA
Cytochrome bd-i ubiquinol oxidase subunit i; A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron
   
 0.998
cydB
Cytochrome bd-i ubiquinol oxidase subunit ii; A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron
  
 0.998
cbdX
Cytochrome bd-ii ubiquinol oxidase subunit appx; Might be part of cytochrome bd-II oxidase (appB and appC). Able to restore reductant resistance to a cydX deletion mutant upon overexpression. CydX and this protein may have some functional overlap
     
 0.974
ynhF
annotation not available
    
 
 0.912
sdhC
Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH)
     
  0.900
sdhD
Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH)
     
  0.900
sdhA
Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth
     
  0.900
sdhB
Succinate:quinone oxidoreductase, iron-sulfur cluster binding protein; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth
     
  0.900
poxB
Pyruvate dehydrogenase, thiamine triphosphate-binding, fad-binding; Belongs to the TPP enzyme family
     
  0.900
ndh
Respiratory nadh dehydrogenase 2/cupric reductase; Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation
     
  0.900
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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